Evidence map›Paper›PMID 10889128›Full record

ArticleCirculation2000

Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?

I Lemieux, A Pascot, C Couillard, B Lamarche, A Tchernof, N Alméras, J Bergeron, D Gaudet, G Tremblay, D Prud'homme and 2 more

Abstract read
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In one paragraph

Article in Circulation, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 259 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
259citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

259 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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199 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

I LemieuxQuebec Heart Institute, Laval Hospital Research Center, Canada.
A Pascot
C Couillard
B Lamarche
A Tchernof
N Alméras
J Bergeron
D Gaudet
G Tremblay
D Prud'homme
A Nadeau
J P Després

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study tested the hypothesis that simple variables, such as waist circumference and fasting plasma triglyceride (TG) concentrations, could be used as screening tools for the identification of men characterized by a metabolic triad of nontraditional risk factors (elevated insulin and apolipoprotein [apo] B and small, dense LDL particles). METHODS AND

resultsResults of the metabolic study (study 1) conducted on 185 healthy men indicate that a large proportion (>80%) of men with waist circumference values >/=90 cm and with elevated TG levels (>/=2.0 mmol/L) were characterized by the atherogenic metabolic triad. Validation of the model in an angiographic study (study 2) on a sample of 287 men with and without coronary artery disease (CAD) revealed that only men with both elevated waist and TG levels were at increased risk of CAD (odds ratio of 3.6, P<0.03) compared with men with low waist and TG levels.

conclusionsIt is suggested that the simultaneous measurement and interpretation of waist circumference and fasting TG could be used as inexpensive screening tools to identify men characterized by the atherogenic metabolic triad (hyperinsulinemia, elevated apo B, small, dense LDL) and at high risk for CAD.

Indexed as

Body CompositionAbdomenAdultApolipoproteins BBiomarkersCoronary AngiographyCoronary Artery DiseaseCoronary DiseaseHumansHyperinsulinismHypertriglyceridemiaLipoproteins, LDLMaleMass ScreeningMiddle AgedPredictive Value of TestsApolipoproteins BBiomarkersLipoproteins, LDLTriglycerides

Identifiers

PMID10889128

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.