Modulation of complement membrane attack by local C7 synthesis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics.Pharmacological reviews · 2021
   Pooled it
2. Integrative multi-omics analysis identifies stellate cell-derived complement component 7 as a predictor of fibrosis and liver-related events in MASLD.JHEP reports : innovation in hepatology · 2026
   Article
3. The grand escape - how pathogens outsmart the human complement system.Immunobiology · 2025
   Review
4. Biomarkers of the Complement System in Cancer.Medeniyet medical journal · 2025
   Article
5. Exploring the causal effect of complement and IgA nephropathy-a Mendelian randomization study.Renal failure · 2024
   Article
6. Comparative Analysis of Digital Transcriptomics Between Pre- and Post-Treatment Samples of Patients with Locally Advanced Cervical Cancer: A Preliminary Study.Current issues in molecular biology · 2024
   Article
7. Complement C7 and clusterin form a complex in circulation.Frontiers in immunology · 2024
   Article
8. Androgen-regulated stromal complement component 7 (C7) suppresses prostate cancer growth.Oncogene · 2023
   Article
9. Hsa_circ_0072309 is a prognostic biomarker and is correlated with immune infiltration in gastric cancer.Heliyon · 2023
   Article
10. Interacting Effects of Sea Louse (Frontiers in immunology · 2022
    Article
11. Functional genetic variants in complement component 7 confer susceptibility to gastric cancer.PeerJ · 2022
    Article
12. Plasma complement C7 as a target in non-small cell lung cancer patients to implement 3P medicine strategies.The EPMA journal · 2021
    Article
13. A Personal Tribute to a Highly Inspiring Mentor, Professor Sir Peter J. Lachmann, 1931-2020.Viruses · 2021
    Article
14. To Kill But Not Be Killed: Controlling the Activity of Mammalian Pore-Forming Proteins.Frontiers in immunology · 2020
    Review
15. Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients.PloS one · 2020
    Article
16. Complement component 7 (C7), a potential tumor suppressor, is correlated with tumor progression and prognosis.Oncotarget · 2016
    Article
17. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited.Progress in retinal and eye research · 2010
    Review
18. Gene duplication of the seventh component of complement in rainbow trout.Immunogenetics · 2005
    Article
19. Deficiencies of the complement MAC II gene cluster (C6, C7, C9): is subtotal C6 deficiency of particular evolutionary benefit?Clinical and experimental immunology · 2003
    Review

Corrections and comments

• Comment on
  The endothelium is an extrahepatic site of synthesis of the seventh component of the complement system.2000

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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