ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2000
Visual responses of neurons in the middle temporal area of new world monkeys after lesions of striate cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 102 citations in OpenAlex.
- What V1 Damage Can Teach Us About Visual Perception and Learning.Annual review of vision science · 2025Review
- Rapid degeneration and neurochemical plasticity of the lateral geniculate nucleus following lesions of the primary visual cortex in marmoset monkeys.Current research in neurobiology · 2025Article
- Transsynaptic Degeneration of Retinal Ganglion Cells Following Lesions to Primary Visual Cortex in Marmosets.Investigative ophthalmology & visual science · 2024Article
- Cortical adaptation of the night monkey to a nocturnal niche environment: a comparative non-invasive T1w/T2w myelin study.Brain structure & function · 2023Article
- Article
- Escaping the nocturnal bottleneck, and the evolution of the dorsal and ventral streams of visual processing in primates.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Remodeling of lateral geniculate nucleus projections to extrastriate area MT following long-term lesions of striate cortex.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The nature of blindsight: implications for current theories of consciousness.Neuroscience of consciousness · 2022Review
- Neurochemical changes in the primate lateral geniculate nucleus following lesions of striate cortex in infancy and adulthood: implications for residual vision and blindsight.Brain structure & function · 2021Article
- Morphological evidence for multiple distinct channels of corticogeniculate feedback originating in mid-level extrastriate visual areas of the ferret.Brain structure & function · 2021Article
- Ancient visual channels have a causal role in arithmetic calculations.Scientific reports · 2021Article
- Volume reduction without neuronal loss in the primate pulvinar complex following striate cortex lesions.Brain structure & function · 2021Article
- Numerosities and Other Magnitudes in the Brains: A Comparative View.Frontiers in psychology · 2021Review
- V1-bypassing thalamo-cortical visual circuits in blindsight and developmental dyslexia.Current opinion in physiology · 2020Article
- Altered Sensitivity to Motion of Area MT Neurons Following Long-Term V1 Lesions.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Article
- Receptive Field Properties of Koniocellular On/Off Neurons in the Lateral Geniculate Nucleus of Marmoset Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Robust Visual Responses and Normal Retinotopy in Primate Lateral Geniculate Nucleus following Long-term Lesions of Striate Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Numerosity representation is encoded in human subcortex.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Nonlinear population receptive field changes in human area V5/MT+ of healthy subjects with simulated visual field scotomas.NeuroImage · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In primates, lesions of striate cortex (V1) result in scotomas in which only rudimentary visual abilities remain. These aspects of vision that survive V1 lesions have been attributed to direct thalamic pathways to extrastriate areas, including the middle temporal area (MT). However, studies in New World monkeys and humans have questioned this interpretation, suggesting that remnants of V1 are responsible for both the activation of MT and residual vision. We studied the visual responses of neurons in area MT in New World marmoset monkeys in the weeks after lesions of V1. The extent of the scotoma in each case was estimated by mapping the receptive fields of cells located near the lesion border and by histological reconstruction. Two response types were observed among the cells located in the part of MT that corresponds, in visuotopic coordinates, to the lesioned part of V1. Many neurons (62%) had receptive fields that were displaced relative to their expected location, so that they represented the visual field immediately surrounding the scotoma. This may be a consequence of a process analogous to the reorganization of the V1 map after retinal lesions. However, another 20% of the cells had receptive fields centered inside the scotoma. Most of these neurons were strongly direction-selective, similar to normal MT cells. These results show that MT cells differ in their responses to lesioning of V1 and that only a subpopulation of MT neurons can be reasonably linked to residual vision and blindsight.
Indexed as
Identifiers
10884339PMC6772324W2129924853What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.