ReviewJournal of mammary gland biology and neoplasia1997
EGF-related peptides and their receptors in mammary gland development.
Review in Journal of mammary gland biology and neoplasia, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 58 citations in OpenAlex.
- Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary Tissue.Journal of lipids · 2013Article
- Met receptor acts uniquely for survival and morphogenesis of EGFR-dependent normal mammary epithelial and cancer cells.PloS one · 2012Article
- Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix.American journal of respiratory cell and molecular biology · 2011Article
- The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium.Carcinogenesis · 2007Article
- Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situ hybridization and immunohistochemistry.Breast cancer research : BCR · 2005Article
- EGF controls the in vivo developmental potential of a mammary epithelial cell line possessing progenitor properties.The Journal of cell biology · 2002Article
- Establishing a framework for the functional mammary gland: from endocrinology to morphology.Journal of mammary gland biology and neoplasia · 2002Review
- Regulation of mouse mammary gland development and tumorigenesis by the ERBB signaling network.Journal of mammary gland biology and neoplasia · 2001Review
- The ErbB receptors as targets for breast cancer therapy.Journal of mammary gland biology and neoplasia · 1999Review
- Article
- Mammary gland development and tumorigenesis in estrogen receptor knockout mice.Journal of mammary gland biology and neoplasia · 1997Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The discovery of multiple EGF-like ligands and erbB receptors offers the potential for a highly diverse signaling system allowing specific ligand/receptor complexes to be created in response to a certain hormone(s) or stage of mammary development. The known erbB receptors and several of the erbB-related ligands are synthesized by the normal mammary gland and have different temporal and spatial expression patterns. For instance, cumulative findings support the concepts that the EGF receptor has an essential role in morphogenesis of the mammary gland and that activation of this receptor occurs in response to estradiol-stimulated synthesis of an EGF receptor ligand in mammary stromal cells. The importance of both epithelial and stromal mammary cells in the hormonal activation of erbB-related pathways is underscored in this review. Current experimental protocols that utilize erbB mutant mice or enable detection of phosphorylated erbB members and their proximal substrates should permit more precise identification of the pathways operative in the mammary gland.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.