ArticleGenetics2000
Combined analyses of data from quantitative trait loci mapping studies. Chromosome 4 effects on porcine growth and fatness.
Article in Genetics, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 138 citations in OpenAlex.
- Meta-analysis of genome-wide association from genomic prediction models.Animal genetics · 2016Pooled it
- Meta - and combined - QTL analysis of different experiments on immune traits in chickens.Journal of applied genetics · 2013Pooled it
- Genome-Wide Association Analysis Identifies Genomic Regions and Candidate Genes for Growth and Fatness Traits in Diannan Small-Ear (DSE) Pigs.Animals : an open access journal from MDPI · 2023Article
- Genome wide association study of thyroid hormone levels following challenge with porcine reproductive and respiratory syndrome virus.Frontiers in genetics · 2023Article
- Using genome wide association studies to identify common QTL regions in three different genetic backgrounds based on Iberian pig breed.PloS one · 2018Article
- A genome-wide association study identifies genomic loci associated with backfat thickness, carcass weight, and body weight in two commercial pig populations.Journal of applied genetics · 2017Article
- How do the type of QTL effect and the form of the residual term influence QTL detection in multi-parent populations? A case study in the maize EU-NAM population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Genome-wide detection of genetic markers associated with growth and fatness in four pig populations using four approaches.Genetics, selection, evolution : GSE · 2017Article
- Regularized quantile regression for SNP marker estimation of pig growth curves.Journal of animal science and biotechnology · 2017Article
- Article
- Genome-wide association analyses reveal significant loci and strong candidate genes for growth and fatness traits in two pig populations.Genetics, selection, evolution : GSE · 2015Article
- Joint linkage QTL analyses for partial resistance to Phytophthora sojae in soybean using six nested inbred populations with heterogeneous conditions.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- Fine mapping of fatness QTL on porcine chromosome X and analyses of three positional candidate genes.BMC genetics · 2013Article
- Mapping quantitative trait loci for T lymphocyte subpopulations in peripheral blood in swine.BMC genetics · 2011Article
- A novel 18-bp deletion mutation of the AMPD1 gene affects carcass traits in Qinchuan cattle.Molecular biology reports · 2010Article
- Combining two Meishan F2 crosses improves the detection of QTL on pig chromosomes 2, 4 and 6.Genetics, selection, evolution : GSE · 2010Article
- Joint QTL analysis of three connected F2-crosses in pigs.Genetics, selection, evolution : GSE · 2010Article
- Article
- Characterization and transcriptional regulation analysis of the porcine TNFAIP8L2 gene.Molecular genetics and genomics : MGG · 2010Article
- Replication and narrowing of gene expression quantitative trait loci using inbred mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2009Article
Corrections and comments
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Authors and funding
14 authors at 9 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For many species several similar QTL mapping populations have been produced and analyzed independently. Joint analysis of such data could be used to increase power to detect QTL and evaluate population differences. In this study, data were collated on almost 3000 pigs from seven different F(2) crosses between Western commercial breeds and either the European wild boar or the Chinese Meishan breed. Genotypes were available for 31 markers on chromosome 4 (on average 8.3 markers per population). Data from three traits common to all populations (birth weight, mean backfat depth at slaughter or end of test, and growth rate from birth to slaughter or end of test) were analyzed for individual populations and jointly. A QTL influencing birth weight was detected in one individual population and in the combined data, with no significant interaction of the QTL effect with population. A QTL affecting backfat that had a significantly greater effect in wild boar than in Meishan crosses was detected. Some evidence for a QTL affecting growth rate was detected in all populations, with no significant differences between populations. This study is the largest F(2) QTL analysis achieved in a livestock species and demonstrates the potential of joint analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.