ReviewJournal of biosciences2000
Dynamical complexity and temporal plasticity in pancreatic beta-cells.
Review in Journal of biosciences, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- The physiological role of β-cell heterogeneity in pancreatic islet function.Nature reviews. Endocrinology · 2022Review
- Bursting dynamics remarkably improve the performance of neural networks on liquid computing.Cognitive neurodynamics · 2016Article
- Development, growth and maintenance of β-cell mass: models are also part of the story.Molecular aspects of medicine · 2015Review
- Article
- The impact of mathematical modeling on the understanding of diabetes and related complications.CPT: pharmacometrics & systems pharmacology · 2013Article
- Slow variable dominance and phase resetting in phantom bursting.Journal of theoretical biology · 2011Article
- Capturing the bursting dynamics of a two-cell inhibitory network using a one-dimensional map.Journal of computational neuroscience · 2007Article
- Voltage-operated calcium channel heterogeneity in pancreatic beta cells: physiopathological implications.Journal of bioenergetics and biomembranes · 2003Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
We discuss some of the biological and mathematical issues involved in understanding and modelling the bursting electrical activity in pancreatic beta-cells. These issues include single-cell versus islet behaviour, parameter heterogeneity, channel noise, the effects of hormones, neurotransmitters, and ions, and multiple slow biophysical processes. Some of the key experimental and modelling studies are described, and some of the major open questions are discussed.
Indexed as
Identifiers
10878861What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.