ReviewDrug safety2000
Fluoroquinolone-induced renal failure.
Review in Drug safety, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 79 citations in OpenAlex.
- Lack of effect of DX-619, a novel des-fluoro(6)-quinolone, on glomerular filtration rate measured by serum clearance of cold iohexol.Antimicrobial agents and chemotherapy · 2007Trial
- Insights into renal and urological complications of inflammatory bowel disease.World journal of nephrology · 2024Review
- An exploratory study evaluated the 30 most commonly reported medications in the United States food and drug administration's adverse event reporting system that are associated with the occurrence of kidney stones.Frontiers in pharmacology · 2024Article
- Indirect Competitive Enzyme-Linked Immunosorbent Assay Based on Broad-Spectrum Antibody for Simultaneous Determination of Thirteen Fluoroquinolone Antibiotics inFoods (Basel, Switzerland) · 2023Article
- Overview of Side-Effects of Antibacterial Fluoroquinolones: New Drugs versus Old Drugs, a Step Forward in the Safety Profile?Pharmaceutics · 2023Review
- The potential effect of infliximab, dimethyl fumarate (DMF), and their combination in ciprofloxacin-induced renal toxicity in male rats.Journal of medicine and life · 2023Article
- The effectiveness of colistin/levofloxacin compared to colistin/meropenem in the treatment of ventilator-associated pneumonia (VAP) caused by carbapenem-resistantResearch in pharmaceutical sciences · 2023Article
- A riddle wrapped in an enigma: acute kidney injury in a girl with Crohn's disease: Answers.Pediatric nephrology (Berlin, Germany) · 2020Article
- Exercise-induced acute renal failure in a trainee cyclist without hypouricemia: Successful athletic career post-treatment.Journal of general and family medicine · 2017Article
- Fluoroquinolone-induced serious, persistent, multisymptom adverse effects.BMJ case reports · 2015Article
- Risk of acute kidney injury associated with the use of fluoroquinolones.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
- Sustained ocular delivery of ciprofloxacin using nanospheres and conventional contact lens materials.Investigative ophthalmology & visual science · 2012Article
- Article
- A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases.The primary care companion for CNS disorders · 2011Article
- Safety considerations of fluoroquinolones in the elderly: an update.Drugs & aging · 2010Review
- Identification of enoxacin as an inhibitor of osteoclast formation and bone resorption by structure-based virtual screening.Journal of medicinal chemistry · 2009Article
- Current therapy of inflammatory bowel disease in children.Paediatric drugs · 2006Review
- Article
- Fluoroquinolones in the elderly: safety considerations.Drugs & aging · 2003Review
- Comparison of the Efficacy of Adding Inhaled Levofloxacin and Colistin to a Basic Regimen of Colistin and Meropenem in the Treatment of Ventilator-associated Pneumonia Caused by Multidrug-resistant Gram-negative Bacteria: A Randomized Open-label Clinical Trial.Journal of research in pharmacy practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluoroquinolones are generally well tolerated, clinically useful antimicrobials. This paper highlights rare, but potentially serious, adverse effects involving the kidney. Other antimicrobials have long been known to cause various forms of nephrotoxicity occurring as allergic interstitial nephritis, granulomatous interstitial nephritis, necrotising vasculitis, allergic tubular nephritis or a tubular necrosis. A Medline search (1985 to May 1999) of ciprofloxacin, norfloxacin, levofloxacin, ofloxacin, trovafloxacin, enoxacin, sparfloxacin, grepafloxacin, gatifloxacin, clinafloxacin and moxifloxacin was conducted to ascertain the incidence and features of fluoroquinolone nephrotoxicity. Unfortunately, the data primarily consist of case reports and temporally related events. The incidence of these adverse effects is hard to estimate, and the cause may be multifactorial. While the use of ciprofloxacin appears to increase the risk, this may be due to its longer and more widespread use when compared with the newer agents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.