Evidence map›Paper›PMID 10875028›Full record

ReviewClinical cardiology2000

Hyperthyroid heart disease.

B M Fadel, S Ellahham, M D Ringel, J Lindsay, L Wartofsky, K D Burman

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical cardiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 170 citations in OpenAlex.

  1. The Effect of Thyroid Function on GDF15 Levels.International journal of molecular sciences · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Effects of gas signaling molecule SOThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  6. Article
  7. Article
  8. Protective role of vitamin D3 in a rat model of hyperthyroid-induced cardiomyopathy.Journal of traditional and complementary medicine · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Decreased gene expression of KInternational journal of clinical and experimental pathology · 2022
    Article
  15. Triad of palpitation, angina, and murmur in a non-cardiac patient.Journal of family medicine and primary care · 2021
    Article
  16. Cardiovascular Events in Patients with Thyroid Storm.Journal of the Endocrine Society · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

B M FadelDivision of Cardiovascular Medicine, Stanford University, California 94305-5406, USA.
S Ellahham
M D Ringel
J Lindsay
L Wartofsky
K D Burman
MedStar Washington Hospital Center · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heart is an organ sensitive to the action of thyroid hormone, and measurable changes in cardiac performance are detected with small variations in thyroid hormone serum concentrations. Most patients with hyperthyroidism experience cardiovascular manifestations, and the most serious complications of hyperthyroidism occur as a result of cardiac involvement. Recent studies provide important insights into the molecular pathways that mediate the action of thyroid hormone on the heart and allow a better understanding of the mechanisms that underlie the hemodynamic and clinical manifestations of hyperthyroidism. Several cardiovascular conditions and drugs can interfere with thyroid hormone levels and may pose a difficulty in interpretation of laboratory data in patients with suspected thyroid heart disease. The focus of this report is a review of the current knowledge of thyroid hormone action on the heart and the clinical and hemodynamic laboratory findings as well as therapeutic management of patients with hyperthyroid heart disease.

Indexed as

Atrial FibrillationHeartHeart DiseasesHeart FailureHumansHyperthyroidismMyocardial ContractionMyocardiumThyroid HormonesThyroxineTriiodothyronineThyroid HormonesThyroxineTriiodothyronine

Identifiers

PMID10875028
PMCPMC6654928
OpenAlexW2168989909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.