ArticleAmerican journal of human genetics2000
An optimized set of human telomere clones for studying telomere integrity and architecture.
Article in American journal of human genetics, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Epigenetic Modeling of Jumping Translocations of 1q Heterochromatin in Acute Myeloid Leukemia After 5'-Azacytidine Treatment.Genes, chromosomes & cancer · 2024Article
- VolcanoFinder: Genomic scans for adaptive introgression.PLoS genetics · 2020Article
- Repo-Man/PP1 regulates heterochromatin formation in interphase.Nature communications · 2017Article
- Molecular cytogenetic analysis of telomere rearrangements.Current protocols in human genetics · 2015Article
- Terminal 18q deletions are stabilized by neotelomeres.Molecular cytogenetics · 2015Article
- 3D organization of telomeres in porcine neutrophils and analysis of LPS-activation effect.BMC cell biology · 2013Article
- The 2q37-deletion syndrome: an update of the clinical spectrum including overweight, brachydactyly and behavioural features in 14 new patients.European journal of human genetics : EJHG · 2013Article
- Diverse mutational mechanisms cause pathogenic subtelomeric rearrangements.Human molecular genetics · 2011Article
- Article
- Multiplex ligation dependent probe amplification (MLPA) for rapid distinction between unique sequence positive and negative marker chromosomes in prenatal diagnosis.Molecular cytogenetics · 2011Article
- Array-based comparative genomic hybridization in ulcerative colitis neoplasia: single non-dysplastic biopsies distinguish progressors from non-progressors.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2010Article
- Replication timing of human telomeres is chromosome arm-specific, influenced by subtelomeric structures and connected to nuclear localization.PLoS genetics · 2010Article
- Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group.Journal of cellular and molecular medicine · 2010Article
- Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human cancer cell line.DNA repair · 2009Article
- Wolf-Hirschhorn syndrome facial dysmorphic features in a patient with a terminal 4p16.3 deletion telomeric to the WHSCR and WHSCR 2 regions.European journal of human genetics : EJHG · 2009Article
- Two mosaic terminal inverted duplications arising post-zygotically: Evidence for possible formation of neo-telomeres.Cell & chromosome · 2008Article
- From microscopes to microarrays: dissecting recurrent chromosomal rearrangements.Nature reviews. Genetics · 2007Review
- Molecular karyotyping in patients with mental retardation using 100K single-nucleotide polymorphism arrays.Journal of medical genetics · 2007Article
- Complex chromosome 17p rearrangements associated with low-copy repeats in two patients with congenital anomalies.Human genetics · 2007Article
- Subtelomeric chromosome rearrangements in children with idiopathic mental retardation: applicability of three molecular-cytogenetic methods.Croatian medical journal · 2006Article
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16 authors.
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Abstract
Telomere-specific clones are a valuable resource for the characterization of chromosomal rearrangements. We previously reported a first-generation set of human telomere probes consisting of 34 genomic clones, which were a known distance from the end of the chromosome ( approximately 300 kb), and 7 clones corresponding to the most distal markers on the integrated genetic/physical map (1p, 5p, 6p, 9p, 12p, 15q, and 20q). Subsequently, this resource has been optimized and completed: the size of the genomic clones has been expanded to a target size of 100-200 kb, which is optimal for use in genome-scanning methodologies, and additional probes for the remaining seven telomeres have been identified. For each clone we give an associated mapped sequence-tagged site and provide distances from the telomere estimated using a combination of fiberFISH, interphase FISH, sequence analysis, and radiation-hybrid mapping. This updated set of telomeric clones is an invaluable resource for clinical diagnosis and represents an important contribution to genetic and physical mapping efforts aimed at telomeric regions.
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