ArticleGenes & development2000
Rearrangement of chromatin domains during development in Xenopus.
Article in Genes & development, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 57 citations in OpenAlex.
- Targeting of the Dosage-Compensated Male X-Chromosome during Early Drosophila Development.Cell reports · 2019Article
- Analysis of embryonic development in the unsequenced axolotl: Waves of transcriptomic upheaval and stability.Developmental biology · 2017Article
- Cell cycle control in the early embryonic development of aquatic animal species.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Review
- The selection and function of cell type-specific enhancers.Nature reviews. Molecular cell biology · 2015Review
- DNA polymorphism and epigenetic marks modulate the affinity of a scaffold/matrix attachment region to the nuclear matrix.European journal of human genetics : EJHG · 2014Article
- Genome-wide microarray analysis of Atlantic cod (Gadus morhua) oocyte and embryo.BMC genomics · 2014Article
- Epigenetic landscape for initiation of DNA replication.Chromosoma · 2014Review
- A requiem to the nuclear matrix: from a controversial concept to 3D organization of the nucleus.Chromosoma · 2014Review
- Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.Nucleic acids research · 2011Article
- Control of DNA replication by cyclin-dependent kinases in development.Results and problems in cell differentiation · 2011Review
- Selective matrix attachment regions in T helper cell subsets support loop conformation in the Ifng gene.Genes and immunity · 2007Article
- Chromatin loop domain organization within the 4q35 locus in facioscapulohumeral dystrophy patients versus normal human myoblasts.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Towards understanding the epigenetics of transcription by chromatin structure and the nuclear matrix.Gene therapy & molecular biology · 2005Article
- The multicoloured world of promoter recognition complexes.The EMBO journal · 2004Review
- Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition.The EMBO journal · 2002Article
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A dynamic change in the organization of different gene domains transcribed by RNA polymerase I, II, or III occurs during the progression from quiescent [pre-midblastula transition (pre-MBT)] to active (post-MBT) embryos during Xenopus development. In the rDNA, c-myc, and somatic 5S gene domains, a transition from random to specific anchorage to the nuclear matrix occurs when chromatin domains become active. The keratin gene domain was also randomly associated to the nuclear matrix before MBT, whereas a defined attachment site was found in keratinocytes. In agreement with this specification, ligation-mediated (LM)-PCR genomic footprinting carried out on the subpopulation of 5S domains specifically attached to the matrix reveals the hallmarks of determined chromatin after the midblastula transition. In contrast, the same analysis performed on the total 5S gene population does not reveal specific chromatin organization, validating the use of nuclear matrix fractionation to unveil active chromatin domains. These data provide a means for the determination of active chromosomal territories in the embryo and emphasize the role of nuclear architecture in regulated gene expression during development.
Indexed as
Identifiers
10859171PMC316689W2161065782What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.