ArticleAntimicrobial agents and chemotherapy2000
Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance.
Article in Antimicrobial agents and chemotherapy, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 131 citations in OpenAlex.
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- Improved mini-TnApplied and environmental microbiology · 2023Article
- Efflux Pump Inhibitors in Controlling Antibiotic Resistance: Outlook under a Heavy Metal Contamination Context.Molecules (Basel, Switzerland) · 2023Review
- Study of Cadmium Metal Resistance inIndian journal of microbiology · 2023Article
- Plant Secondary Metabolites on Efflux-Mediated Antibiotic ResistantAntibiotics (Basel, Switzerland) · 2023Article
- A guide toFrontiers in cellular and infection microbiology · 2023Review
- The key environmental influencing factors for the change of sediment bacterial community and antibiotics resistance genes in a long-term polluted lake, China.Ecotoxicology (London, England) · 2021Article
- Antimicrobial susceptibility pattern ofAfrican health sciences · 2020Article
- Transferable Mechanisms of Quinolone Resistance from 1998 Onward.Clinical microbiology reviews · 2019Review
- Antimicrobial Resistance inMicrobiology spectrum · 2018Article
- Detection of Bacillus and Stenotrophomonas species growing in an organic acid and endocrine-disrupting chemical-rich environment of distillery spent wash and its phytotoxicity.Environmental monitoring and assessment · 2017Article
- Resistance to Macrolide Antibiotics in Public Health Pathogens.Cold Spring Harbor perspectives in medicine · 2016Review
- Influence of Chicken Manure Fertilization on Antibiotic-Resistant Bacteria in Soil and the Endophytic Bacteria of Pakchoi.International journal of environmental research and public health · 2016Article
- Design a cadA-targeted DNA probe for screening of potential bacterial cadmium biosorbents.Environmental science and pollution research international · 2016Article
- Genomic Potential of Stenotrophomonas maltophilia in Bioremediation with an Assessment of Its Multifaceted Role in Our Environment.Frontiers in microbiology · 2016Review
- Comparative Genomics of Environmental and Clinical Stenotrophomonas maltophilia Strains with Different Antibiotic Resistance Profiles.Genome biology and evolution · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A cluster of genes involved in antibiotic and heavy metal resistance has been characterized from a clinical isolate of the gram-negative bacterium Stenotrophomonas maltophilia. These genes include a macrolide phosphotransferase (mphBM) and a cadmium efflux determinant (cadA), together with the gene cadC coding for its transcriptional regulator. The cadC cadA region is flanked by a truncated IS257 sequence and a region coding for a bin3 invertase. Despite their presence in a gram-negative bacterium, these genetic elements share a common gram-positive origin. The possible origin of these determinants as a remnant composite transposon as well as the role of gene transfer between gram-positive and gram-negative bacteria for the acquisition of antibiotic resistance determinants in chronic, mixed infections is discussed.
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