ArticleGenome research2000
The complete mitochondrial DNA sequence of Scenedesmus obliquus reflects an intermediate stage in the evolution of the green algal mitochondrial genome.
Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 111 citations in OpenAlex.
- Characterization of the complete mitochondrial genome of the green algaMitochondrial DNA. Part B, Resources · 2026Article
- Comprehensive sampling of mitochondrial genomes substantiates the Neoproterozoic origin of land plants.Plant communications · 2025Article
- Long-Read-Based Hybrid Genome Assembly and Annotation of Snow Algal Strain CCCryo 101-99 (cf. Sphaerocystis sp., Chlamydomonadales).Genome biology and evolution · 2024Article
- Origin of minicircular mitochondrial genomes in red algae.Nature communications · 2023Article
- New Dielis species and structural dichotomy of the mitochondrial cox2 gene in Scoliidae wasps.Scientific reports · 2023Article
- Characterization of the mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2023Article
- Structure and Phylogeny of Chloroplast and Mitochondrial Genomes of a Chlorophycean AlgaeLife (Basel, Switzerland) · 2022Article
- Effect ofJournal of microbiology and biotechnology · 2022Article
- Mitochondrial mRNA Processing in the Chlorophyte AlgaPlants (Basel, Switzerland) · 2021Article
- Genome sequencing, assembly, and annotation of the self-flocculating microalga Scenedesmus obliquus AS-6-11.BMC genomics · 2020Article
- Complete mitogenomes of the chlorophycean green algaeMitochondrial DNA. Part B, Resources · 2020Article
- Evolution and Unprecedented Variants of the Mitochondrial Genetic Code in a Lineage of Green Algae.Genome biology and evolution · 2019Article
- Rapid Genetic Code Evolution in Green Algal Mitochondrial Genomes.Molecular biology and evolution · 2019Article
- Novel genetic code and record-setting AT-richness in the highly reduced plastid genome of the holoparasitic plantProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Raphidocelis subcapitata (=Pseudokirchneriella subcapitata) provides an insight into genome evolution and environmental adaptations in the Sphaeropleales.Scientific reports · 2018Article
- Comparative mitochondrial genomics of cryptophyte algae: gene shuffling and dynamic mobile genetic elements.BMC genomics · 2018Article
- Polycytidylation of mitochondrial mRNAs in Chlamydomonas reinhardtii.Nucleic acids research · 2017Article
- Intercompartmental Piecewise Gene Transfer.Genes · 2017Review
- Evolutionarily recent, insertional fission of mitochondrial cox2 into complementary genes in bilaterian Metazoa.BMC genomics · 2017Article
- The complete mitochondrial DNA sequence of the green algaeMitochondrial DNA. Part B, Resources · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two distinct mitochondrial genome types have been described among the green algal lineages investigated to date: a reduced-derived, Chlamydomonas-like type and an ancestral, Prototheca-like type. To determine if this unexpected dichotomy is real or is due to insufficient or biased sampling and to define trends in the evolution of the green algal mitochondrial genome, we sequenced and analyzed the mitochondrial DNA (mtDNA) of Scenedesmus obliquus. This genome is 42,919 bp in size and encodes 42 conserved genes (i.e., large and small subunit rRNA genes, 27 tRNA and 13 respiratory protein-coding genes), four additional free-standing open reading frames with no known homologs, and an intronic reading frame with endonuclease/maturase similarity. No 5S rRNA or ribosomal protein-coding genes have been identified in Scenedesmus mtDNA. The standard protein-coding genes feature a deviant genetic code characterized by the use of UAG (normally a stop codon) to specify leucine, and the unprecedented use of UCA (normally a serine codon) as a signal for termination of translation. The mitochondrial genome of Scenedesmus combines features of both green algal mitochondrial genome types: the presence of a more complex set of protein-coding and tRNA genes is shared with the ancestral type, whereas the lack of 5S rRNA and ribosomal protein-coding genes as well as the presence of fragmented and scrambled rRNA genes are shared with the reduced-derived type of mitochondrial genome organization. Furthermore, the gene content and the fragmentation pattern of the rRNA genes suggest that this genome represents an intermediate stage in the evolutionary process of mitochondrial genome streamlining in green algae.
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