Evidence map›Paper›PMID 10852893›Full record

ArticleJournal of bacteriology2000

The length of the combined 3' untranslated region and poly(A) tail does not control rates of glyceraldehyde-3-phosphate dehydrogenase mRNA translation in three species of parasitic protists.

B H ter Kuile, F J Sallés

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. pH regulation in glycosomes of procyclic formThe Journal of biological chemistry · 2017
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

B H ter KuileThe Rockefeller University, New York, New York 10021-6399, USA. b.terkuile@chem.leidenu niv.nl
F J Sallés
Rockefeller University · USStony Brook University · US

Funding

ADAPTION OF CARBOHYDRATE METABOLISM IN PROTOZOAR29AI034981 · NIAID · ROCKEFELLER UNIVERSITY · PI TER KUILE, BENNO H · 1994 to 1998
–
NIAID NIH HHS 1 R29 AI34981NIGMS NIH HHS 2R01 GM158405
6 · The paper itself

Abstract

Experimental observations suggested that the length of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA 3' end has a role in regulating rates of translation in the parasitic protists Trypanosoma brucei, Leishmania donovani, and Trichomonas vaginalis. Using a PCR assay for poly(A) tail length, we measured the size of the RNA 3' end under different growth conditions in all three species. Our results showed that the combined 3' untranslated region and poly(A) tail of GAPDH mRNA do not vary with different rates of translation.

Indexed as

Protein Biosynthesis3' Untranslated RegionsAnimalsGlyceraldehyde-3-Phosphate DehydrogenasesLeishmania donovaniPoly APolymerase Chain ReactionRNA, MessengerRNA, ProtozoanTrichomonas vaginalisTrypanosoma brucei brucei3' Untranslated RegionsGlyceraldehyde-3-Phosphate DehydrogenasesPoly ARNA, MessengerRNA, Protozoan

Identifiers

PMID10852893
PMCPMC101970
OpenAlexW2113437555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.