Evidence map›Paper›PMID 10837671›Full record

ArticleAdvanced drug delivery reviews1998

Mechanisms of enveloped virus entry into animal cells.

Klasse, Bron, Marsh

Abstract read
In one paragraph

Article in Advanced drug delivery reviews, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Basic Virology.Advances in experimental medicine and biology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Sarco/Endoplasmic Reticulum CaJournal of virology · 2021
    Article
  8. Interactions of SARS-CoV-2 with the Blood-Brain Barrier.International journal of molecular sciences · 2021
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Antiviral immunity in crustaceans.Fish & shellfish immunology · 2009
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. A capsid protein of nonenveloped Bluetongue virus exhibits membrane fusion activity.Proceedings of the National Academy of Sciences of the United States of America · 2004
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

KlasseMedical Research Council Laboratory for Molecular Cell Biology, and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
Bron
Marsh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of viruses to transfer macromolecules between cells makes them attractive starting points for the design of biological delivery vehicles. Virus-based vectors and sub-viral systems are already finding biotechnological and medical applications for gene, peptide, vaccine and drug delivery. Progress has been made in understanding the cellular and molecular mechanisms underlying virus entry, particularly in identifying virus receptors. However, receptor binding is only a first step and we now have to understand how these molecules facilitate entry, how enveloped viruses fuse with cells or non-enveloped viruses penetrate the cell membrane, and what happens following penetration. Only through these detailed analyses will the full potential of viruses as vectors and delivery vehicles be realised. Here we discuss aspects of the entry mechanisms for several well-characterised viral systems. We do not attempt to provide a fully comprehensive review of virus entry but focus primarily on enveloped viruses.

Identifiers

PMID10837671
PMCPMC7125647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.