Trial reportJournal of clinical microbiology2000
Comparison of recoveries of mycobacterium tuberculosis using the automated BACTEC MGIT 960 system, the BACTEC 460 TB system, and Löwenstein-Jensen medium.
Trial report in Journal of clinical microbiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Symptom- and chest-radiography screening for active pulmonary tuberculosis in HIV-negative adults and adults with unknown HIV status.The Cochrane database of systematic reviews · 2022Pooled it
- Meta-analysis of BACTEC MGIT 960 and BACTEC 460 TB, with or without solid media, for detection of mycobacteria.Journal of clinical microbiology · 2004Pooled it
- A time-to-event pharmacodynamic model describing treatment response in patients with pulmonary tuberculosis using days to positivity in automated liquid mycobacterial culture.Antimicrobial agents and chemotherapy · 2013Trial
- Utility of RGM medium for recovery ofIranian journal of microbiology · 2026Article
- A new strategy for the diagnosis of tuberculosis based on secreted antigens: evaluation of the efficacy of alveolar lavage ESAT-6 and CFP-10 tests.European journal of medical research · 2025Article
- Isolation and Antibiotic Resistance Rates ofInfectious diseases & clinical microbiology · 2024Article
- The utility of immunohistochemistry for detecting mycobacterial infections in bronchoalveolar lavage & bronchial washings.The Indian journal of medical research · 2023Article
- Use of Whole-Genome Sequencing to PredictMicrobiology spectrum · 2022Article
- Establishment and validation of a predictive model for nontuberculous mycobacterial infections in acid-fast bacilli smear-positive patients.The clinical respiratory journal · 2021Article
- Impact of nucleic acid amplification test on pulmonary tuberculosis notifications and treatments in Taiwan: a 7-year single-center cohort study.BMC infectious diseases · 2019Article
- Evaluation of a manual identification system for detection of Mycobacterium tuberculosis in a primary tuberculosis laboratory in China.The Journal of international medical research · 2019Article
- Sensitivity and specificity of routine diagnostic work-up for tuberculosis in lung clinics in Yogyakarta, Indonesia: a cohort study.BMC public health · 2019Article
- Sensitivity and specificity of an electronic nose in diagnosing pulmonary tuberculosis among patients with suspected tuberculosis.PloS one · 2019Article
- Evaluation of manual Mycobacterium growth indicator tube for isolation and susceptibility testing ofMedical journal, Armed Forces India · 2018Article
- Performance of the TB-LAMP diagnostic assay in reference laboratories: Results from a multicentre study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2018Article
- Symptom screening for active tuberculosis in pregnant women living with HIV.The Cochrane database of systematic reviews · 2018Article
- Performance of Mycobacterium Growth Indicator Tube BACTEC 960 with Lowenstein-Jensen method for diagnosis of Mycobacterium tuberculosis at Ethiopian National Tuberculosis Reference Laboratory, Addis Ababa, Ethiopia.BMC research notes · 2017Article
- Evaluation of the efficacy of Myco/F lytic system, MGIT960 system and Lowenstein-Jensen medium for recovery of Mycobacterium tuberculosis from sterile body fluids.Scientific reports · 2016Article
- Fast and Inexpensive Detection of Bacterial Viability and Drug Effectiveness through Metabolic Monitoring.Sensors (Basel, Switzerland) · 2016Article
- Evaluation of a liquid culture system in the detection of mycobacteria at an antituberculosis institution in China; A retrospective study.The Journal of international medical research · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Using two different liquid media and one conventional solid medium, a total of 57 mycobacterial isolates (Mycobacterium tuberculosis, n = 55; nontuberculous mycobacteria, n = 2) were recovered from 377 clinical specimens. The rates of recovery of M. tuberculosis were 96. 4% with the BACTEC MGIT 960 liquid medium, 92.7% with BACTEC 12B liquid medium, and 81.8% with the Löwenstein-Jensen (LJ) medium. The mean time to detection of M. tuberculosis in smear-positive specimens was 12.6 days for BACTEC MGIT 960 medium, 13.8 days for BACTEC 12B medium, and 20.1 days for LJ medium, and in smear-negative specimens it was 15.8 days for BACTEC MGIT 960 medium, 17.7 days for BACTEC 12B medium, and 42.2 days for LJ medium. The rates of contamination were 3.7, 2.9, and 1.2% for the BACTEC MGIT 960, BACTEC 12B, and LJ media, respectively. In conclusion, the nonradiometric, fully automated 7-ml BACTEC MGIT 960 system can be considered a viable alternative to the semiautomated, radiometric BACTEC 460 TB system.
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