Evidence map›Paper›PMID 10834967›Full record

ArticleJournal of clinical microbiology2000

Macrorestriction fingerprinting of "Streptococcus milleri" group bacteria by pulsed-field gel electrophoresis.

K L Bartie, M J Wilson, D W Williams, M A Lewis

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

K L BartieDepartment of Oral Surgery, Medicine and Pathology, University of Wales College of Medicine, Cardiff CF14 4XY, United Kingdom.
M J Wilson
D W Williams
M A Lewis
University of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although isolates of the "Streptococcus milleri" group (SMG) of bacteria are regarded as members of the commensal microflora of the body, they are frequently encountered in purulent infections from a range of body sites. The genetic diversity of 91 epidemiologically unrelated SMG isolates (including 37 commensal strains and 49 disease-associated strains) was analyzed by macrorestriction fingerprinting (MF). The genomes were digested with SmaI and ApaI independently, and fragments were resolved by pulsed-field gel electrophoresis. Similarities between banding profiles were determined, and strains were clustered on this basis into dendrograms. In common with other commensal species that have been examined by MF, considerable genetic diversity was revealed. In addition, the clustering of strains tended to support the current taxonomic position of this heterogeneous group. The present study has shown that MF is a powerful tool for characterization of SMG strains and that its use is likely to be of great value in epidemiological and population genetic studies of this group of bacteria.

Indexed as

Polymorphism, Restriction Fragment LengthDeoxyribonucleases, Type II Site-SpecificDNA, BacterialDNA FingerprintingElectrophoresis, Gel, Pulsed-FieldGenome, BacterialGenotypeHumansSpecies SpecificityStreptococcal InfectionsStreptococcusCCCGGG-specific type II deoxyribonucleasesDeoxyribonucleases, Type II Site-SpecificDNA, BacterialGGGCCC-specific type II deoxyribonucleases

Identifiers

PMID10834967
PMCPMC86748
OpenAlexW2159994795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.