ReviewJournal of mammary gland biology and neoplasia1998
Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype.
Review in Journal of mammary gland biology and neoplasia, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 88 citations in OpenAlex.
- Fast ICCD-based temperature modulated fluorescence tomography.Applied optics · 2023Article
- How 3D Printing Is Reshaping Translational Research.Frontiers in bioengineering and biotechnology · 2021Article
- Article
- Tumor Cells Develop Defined Cellular Phenotypes After 3D-Bioprinting in Different Bioinks.Cells · 2019Article
- In Vitro Models for Studying Invasive Transitions of Ductal Carcinoma In Situ.Journal of mammary gland biology and neoplasia · 2019Review
- Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments.Stem cells translational medicine · 2018Article
- An Emergence Framework of Carcinogenesis.Frontiers in oncology · 2017Article
- Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments.The international journal of biochemistry & cell biology · 2016Article
- Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor.Respiratory research · 2016Article
- Dynamic reciprocity between cells and their microenvironment in reproduction.Biology of reproduction · 2015Review
- Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia.Current molecular biology reports · 2015Review
- NF-κB regulates radioresistance mediated by β1-integrin in three-dimensional culture of breast cancer cells.Cancer research · 2013Article
- Three-dimensional cultures of mouse mammary epithelial cells.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Co-implanting orthotopic tissue creates stroma microenvironment enhancing growth and angiogenesis of multiple tumors.F1000Research · 2013Article
- Three-dimensional culture of human breast epithelial cells: the how and the why.Methods in molecular biology (Clifton, N.J.) · 2013Article
- A potential role of progestin-induced laminin-5/α6-integrin signaling in the formation of side branches in the mammary gland.Endocrinology · 2012Article
- Article
- The growth pattern of transplanted normal and nodular hepatocytes.Histochemistry and cell biology · 2011Article
- Apoptotic cell signaling in cancer progression and therapy.Integrative biology : quantitative biosciences from nano to macro · 2011Review
- Synthetic adipose tissue models for studying mammary gland development and breast tissue engineering.Journal of mammary gland biology and neoplasia · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Historically, the study of normal human breast function and breast disorders has been significantly impaired by limitations inherent to available model systems. Recent improvements in human breast epithelial cell lines and three-dimensional (3-D)3 culture systems have contributed to the development of in vitro model systems that recapitulate differentiated epithelial cell phenotypes with remarkable fidelity. Molecular characterization of these human breast cell models has demonstrated that normal breast epithelial cell behavior is determined in part by the precise interplay that exists between a cell and its surrounding microenvironment. Recent functional studies of integrins in a human model system provide evidence to support the idea that the structural stability afforded by integrin-mediated cell-extracellular matrix interactions is an important determinant of normal cellular behavior, and that alterations in tissue structure can give rise to tumorigenic progression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.