ReviewJournal of mammary gland biology and neoplasia1998
The potential influence of radiation-induced microenvironments in neoplastic progression.
Review in Journal of mammary gland biology and neoplasia, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Article
- Understanding the Role of Fibroblasts following a 3D Tumoroid Implantation for Breast Tumor Formation.Bioengineering (Basel, Switzerland) · 2021Review
- Modeling chemical effects on breast cancer: the importance of the microenvironment in vitro.Integrative biology : quantitative biosciences from nano to macro · 2020Review
- Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors.Frontiers in molecular biosciences · 2019Article
- Mouse models for radiation-induced cancers.Mutagenesis · 2016Review
- HZE Radiation Non-Targeted Effects on the Microenvironment That Mediate Mammary Carcinogenesis.Frontiers in oncology · 2016Review
- Identifying new small molecule anti-invasive compounds for glioma treatment.Cell cycle (Georgetown, Tex.) · 2013Review
- Mitigating effects of L-selenomethionine on low-dose iron ion radiation-induced changes in gene expression associated with cellular stress.Oncology letters · 2013Article
- New biological insights on the link between radiation exposure and breast cancer risk.Journal of mammary gland biology and neoplasia · 2013Review
- Radiotherapy-induced malignancies: review of clinical features, pathobiology, and evolving approaches for mitigating risk.Frontiers in oncology · 2013Article
- Mouse models for efficacy testing of agents against radiation carcinogenesis—a literature review.International journal of environmental research and public health · 2012Review
- Interconnected contribution of tissue morphogenesis and the nuclear protein NuMA to the DNA damage response.Journal of cell science · 2012Article
- Stromal mediation of radiation carcinogenesis.Journal of mammary gland biology and neoplasia · 2010Review
- Radiation carcinogenesis in context: how do irradiated tissues become tumors?Health physics · 2009Review
- Seed in soil, with an epigenetic view.Biochimica et biophysica acta · 2009Review
- Transforming growth factor-beta in breast cancer: too much, too late.Breast cancer research : BCR · 2009Review
- Migratory neighbors and distant invaders: tumor-associated niche cells.Genes & development · 2008Review
- Breast cancer: origins and evolution.The Journal of clinical investigation · 2007Review
- Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors.Breast cancer research : BCR · 2007Article
- New highlights on stroma-epithelial interactions in breast cancer.Breast cancer research : BCR · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Ionizing radiation is a complete carcinogen, able both to initiate and promote neoplastic progression and is a known carcinogen of human and murine mammary gland. Tissue response to radiation is a composite of genetic damage, cell death and induction of new gene expression patterns. Although DNA damage is believed to initiate carcinogenesis, the contribution of these other aspects of radiation response are beginning to be explored. Our studies demonstrate that radiation elicits rapid and persistent global alterations in the mammary gland microenvironment. We postulate that radiation-induced microenvironments may affect epithelial cells neoplastic transformation by altering their number or susceptibility. Alternatively, radiation induced microenvironments may exert a selective force on initiated cells and/or be conducive to progression. A key impetus for these studies is the possibility that blocking these events could be a strategy to interrupt neoplastic progression.
Indexed as
Identifiers
10819525What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.