ReviewJournal of mammary gland biology and neoplasia1998
The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland.
Review in Journal of mammary gland biology and neoplasia, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Article
- Mammary gland development--It's not just about estrogen.Journal of dairy science · 2016Review
- Stromal-epithelial cell interactions and alteration of branching morphogenesis in macromastic mammary glands.Journal of cellular and molecular medicine · 2014Article
- Effects of steroid hormones on differentiated glandular epithelial and stromal cells in a three dimensional cell culture model of the canine endometrium.BMC veterinary research · 2013Article
- Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer.Endocrine reviews · 2013Review
- Preparation of epithelial and mesenchymal stem cells from murine mammary gland.Current protocols in toxicology · 2011Article
- An immunohistochemical method to study breast cancer cell subpopulations and their growth regulation by hormones in three-dimensional cultures.Frontiers in endocrinology · 2011Article
- Transcriptome analysis of epithelial and stromal contributions to mammogenesis in three week prepartum cows.PloS one · 2011Article
- Conditional knockout of fibronectin abrogates mouse mammary gland lobuloalveolar differentiation.Developmental biology · 2010Article
- Isolation of mammary-specific extracellular matrix to assess acute cell-ECM interactions in 3D culture.Journal of mammary gland biology and neoplasia · 2010Article
- Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone-independent growth of estrogen receptor-positive breast cancer.Cancer research · 2010Article
- IGF-I, GH, and sex steroid effects in normal mammary gland development.Journal of mammary gland biology and neoplasia · 2008Article
- Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland.Journal of cellular physiology · 2008Article
- Amphiregulin: role in mammary gland development and breast cancer.Journal of mammary gland biology and neoplasia · 2008Review
- Progestin-regulated luminal cell and myoepithelial cell-specific responses in mammary organoid culture.Endocrinology · 2008Article
- Estrogen receptors inhibit Smad3 transcriptional activity through Ap-1 transcription factors.Molecular and cellular biochemistry · 2007Article
- Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Article
- Early onset of puberty and early ovarian failure in CYP7B1 knockout mice.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation.Journal of cell science · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Postnatal mammary gland development is highly dependent on the ovarian steroids, estrogen and progesterone. However, evidence from both in vitro and in vivo studies indicates that steroid-induced development occurs indirectly, requiring stromal cooperation in epithelial proliferation and morphogenesis. Stromal cells appear to influence epithelial cell behavior by secretion of growth factors and/or by altering the composition of the extracellular matrix in which epithelial cells reside. This review will discuss the requirement for stromal tissue in modulating proliferative responses to ovarian hormones during postnatal development and the potential role of the EGF, IGF, HGF and FGF3 growth factor families. Additionally, the roles of extracellular matrix proteins, including fibronectin, collagens and laminin, will be summarized.
Indexed as
Identifiers
10819522What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.