ReviewJournal of mammary gland biology and neoplasia1998
Transferrin and prolactin transcytosis in the lactating mammary epithelial cell.
Review in Journal of mammary gland biology and neoplasia, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 48 citations in OpenAlex.
- Transporters and drug secretion into human breast milk.Expert opinion on drug metabolism & toxicology · 2025Review
- Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome.The Journal of nutrition · 2021Observational
- The Functional Power of the Human Milk Proteome.Nutrients · 2019Review
- Proteolytic Systems in Milk: Perspectives on the Evolutionary Function within the Mammary Gland and the Infant.Journal of mammary gland biology and neoplasia · 2015Review
- Milk secretion: The role of SNARE proteins.Journal of mammary gland biology and neoplasia · 2014Review
- Colostrogenesis: IgG1 transcytosis mechanisms.Journal of mammary gland biology and neoplasia · 2014Review
- The Immunology of Mammary Gland of Dairy Ruminants between Healthy and Inflammatory Conditions.Journal of veterinary medicine · 2014Review
- Prolactin promotes the secretion of active cathepsin D at the basal side of rat mammary acini.Endocrinology · 2008Article
- Paradigm-shifters: phosphorylated prolactin and short prolactin receptors.Journal of mammary gland biology and neoplasia · 2008Review
- What can we learn from rodents about prolactin in humans?Endocrine reviews · 2008Review
- Gene regulatory networks in lactation: identification of global principles using bioinformatics.BMC systems biology · 2007Article
- Epimorphin mediates mammary luminal morphogenesis through control of C/EBPbeta.The Journal of cell biology · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mammary epithelial cell ferries constituents originating from blood and from stromal cells, into milk, by transcytosis. Morphological analysis of a membrane marker of transcytosis in the lactating mammary epithelial cell showed that very rapid endocytosis of surface membrane occurs from both the basolateral and the apical side of the cell. In both cases, membrane trafficking between endosomes and the Golgi complex allows communication between the endocytic and the biosynthetic pathways. Transferrin and prolactin are internalized in mammary cells and transported through multivesicular bodies and Golgi stacks. They are released into milk via different types of secretory vesicles, prolactin being carried in secretory vesicles containing casein micelles. Consequences of the intracellular transport of these proteins and physiological benefits for cell function are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.