ReviewJournal of mammary gland biology and neoplasia1998
Use of the autopsy to study ontogeny and expression of the estrogen receptor gene in human breast.
Review in Journal of mammary gland biology and neoplasia, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 43 citations in OpenAlex.
- Defining breast epithelial cell types in the single-cell era.Developmental cell · 2025Review
- Role of Secreted Frizzled-Related Protein 1 in Early Breast Carcinogenesis and Breast Cancer Aggressiveness.Cancers · 2023Article
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- Minireview: Progesterone Regulation of Proliferation in the Normal Human Breast and in Breast Cancer: A Tale of Two Scenarios?Molecular endocrinology (Baltimore, Md.) · 2015Review
- Article
- Urban-rural differences in breast cancer incidence by hormone receptor status across 6 years in Egypt.Breast cancer research and treatment · 2010Article
- The Mammary Glands of Macaques.Toxicologic pathology · 2008Article
- Expression of estrogen receptor alpha and beta in breast cancers of pre- and post-menopausal women.Pathology oncology research : POR · 2008Article
- Normal breast stem cells, malignant breast stem cells, and the perinatal origin of breast cancer.Stem cell reviews · 2006Review
- Steroid receptors and cell cycle in normal mammary epithelium.Journal of mammary gland biology and neoplasia · 2004Review
- Establishing a framework for the functional mammary gland: from endocrinology to morphology.Journal of mammary gland biology and neoplasia · 2002Review
- Human breast development.Journal of mammary gland biology and neoplasia · 2000Review
- Regulation of mammary gland growth and morphogenesis by the mammary fat pad: a species comparison.Journal of mammary gland biology and neoplasia · 1999Review
- The comparative pathology of human and mouse mammary glands.Journal of mammary gland biology and neoplasia · 1999Review
- The mammary fat pad.Journal of mammary gland biology and neoplasia · 1998Review
- Are the TDLU of the human the same as the LA of mice?Journal of mammary gland biology and neoplasia · 1998Article
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1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Historically, autopsies have been a valuable resource for morphologic studies of the human breast, and have been used in conjunction with radiologic evaluation and epidemiology to provide information about population prevalence of pre-malignant and malignant disease. More recently, well-preserved post-mortem breast tissue has also been used to evaluate the status of genes and their expression. Using molecular techniques and immunohistochemistry, quantitation of gene expression and localization of proteins of hormone receptors, growth factor receptors, growth factors, cell-proliferation related antigens and proto-oncogenes can be evaluated in autopsy-derived breast tissue. Expression of the estrogen receptor (ER)3 gene at the mRNA and protein product levels has been evaluated in breast tissue from infants, children, adolescent girls, and adult women in various phases of the menstrual cycle, pregnancy and post-menopausal. The results of these studies support a role for the ER gene in early as well as pubescent breast development, and also in normal cyclical and abnormal cell proliferation in the terminal-duct-lobular-units (TDLU) of adult women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.