ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners1999
Conducting randomized trials in general practice: methodological and practical issues.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What works to recruit general practices to trials? A rapid review.HRB open research · 2023Pooled it
- Trial
- Baseline characteristics and comparability of older multimorbid patients with polypharmacy and general practitioners participating in a randomized controlled primary care trial.BMC family practice · 2021Trial
- An Approach to Assess Generalizability in Comparative Effectiveness Research: A Case Study of the Whole Systems Demonstrator Cluster Randomized Trial Comparing Telehealth with Usual Care for Patients with Chronic Health Conditions.Medical decision making : an international journal of the Society for Medical Decision Making · 2015Trial
- Identifying strategies to maximise recruitment and retention of practices and patients in a multicentre randomised controlled trial of an intervention to optimise secondary prevention for coronary heart disease in primary care.BMC medical research methodology · 2009Trial
- Buprenorphine versus dihydrocodeine for opiate detoxification in primary care: a randomised controlled trial.BMC family practice · 2007Trial
- Clinical trial recruitment in primary care: exploratory factor analysis of a questionnaire to measure barriers and facilitators to primary care providers' involvement.BMC primary care · 2022Article
- Article
- Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): Recruiting Primary Care Research Sites-the PLEASANT experience.NPJ primary care respiratory medicine · 2015Article
- Results from a trial of an unsupported internet intervention for depressive symptoms.Internet interventions · 2014Article
- An evaluation of the effectiveness of recruitment methods: the staying well after depression randomized controlled trial.Clinical trials (London, England) · 2014Article
- The SCIDOTS Project: evidence of benefits of an integrated tobacco cessation intervention in tuberculosis care on treatment outcomes.Substance abuse treatment, prevention, and policy · 2011Article
- A clinical trial alert tool to recruit large patient samples and assess selection bias in general practice research.BMC medical research methodology · 2011Article
- GP Participation and Recruitment of Patients to RCTs: Lessons from Trials of Acupuncture and Exercise for Low Back Pain in Primary Care.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Methodological considerations for a randomised controlled trial of podiatry care in rheumatoid arthritis: lessons from an exploratory trial.BMC musculoskeletal disorders · 2007Article
- Coping with methodological dilemmas; about establishing the effectiveness of interventions in routine medical practice.BMC health services research · 2006Article
- Investigator barriers and preferences to conduct clinical drug trials in Finland: a qualitative study.Pharmacy world & science : PWS · 2003Article
- [Why are so few clinical trials run in primary care?].Atencion primaria · 2002Review
- Randomised controlled trials in primary care: case study.BMJ (Clinical research ed.) · 2000Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evaluation of the outcome of health services technologies is a requirement for their efficient provision in clinical practice. The most reliable evidence for treatment efficacy comes from randomized trials. Randomized trials in general practice pose particular methodological and practical difficulties. In this paper, we discuss how best to plan and manage a clinical trial in this setting. We base our discussion on our experience of conducting randomized trials to evaluate the effectiveness of brief psychotherapy in general practice.
Indexed as
Identifiers
10818663PMC1313568What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.