ArticleInfection and immunity2000
Bacterial cell wall-induced arthritis: chemical composition and tissue distribution of four Lactobacillus strains.
Article in Infection and immunity, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 57 citations in OpenAlex.
- Periodontal Treatment for Chronic Periodontitis With Rheumatoid Arthritis.International dental journal · 2022Trial
- Periodontal therapy reduces the severity of active rheumatoid arthritis in patients treated with or without tumor necrosis factor inhibitors.Journal of periodontology · 2009Trial
- Gut-Joint Axis: Impact of Bifidobacterial Cell Wall Lipoproteins on Arthritis Development.Nutrients · 2023Article
- Article
- The Gut Microbiota and Respiratory Diseases: New Evidence.Journal of immunology research · 2020Review
- Article
- Biomimetically Engineered Demi-Bacteria Potentiate Vaccination against Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017Article
- Rheumatoid arthritis - an update for general dental practitioners.British dental journal · 2016Article
- Probiotic bacteria: a viable adjuvant therapy for relieving symptoms of rheumatoid arthritis.Inflammopharmacology · 2016Review
- Analysis of fecal Lactobacillus community structure in patients with early rheumatoid arthritis.Current microbiology · 2013Article
- Lectin microarray reveals binding profiles of Lactobacillus casei strains in a comprehensive analysis of bacterial cell wall polysaccharides.Applied and environmental microbiology · 2011Article
- Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Immunoglobulin G and A antibody responses to Bacteroides forsythus and Prevotella intermedia in sera and synovial fluids of arthritis patients.Clinical and diagnostic laboratory immunology · 2003Article
- Role of peptidoglycan subtypes in the pathogenesis of bacterial cell wall arthritis.Annals of the rheumatic diseases · 2003Article
- Muramic acid is not generally present in the human spleen as determined by gas chromatography-tandem mass spectrometry.Infection and immunity · 2002Article
- Enzyme degradation and proinflammatory activity in arthritogenic and nonarthritogenic Eubacterium aerofaciens cell walls.Infection and immunity · 2001Article
- Influence of major histocompatibility complex on bacterial composition of fecal flora.Infection and immunity · 2001Article
- Characterisation of Eubacterium cell wall: peptidoglycan structure determines arthritogenicity.Annals of the rheumatic diseases · 2001Article
- Effect of periodontal therapy on disease activity in patients of rheumatoid arthritis with chronic periodontitis.Journal of oral biology and craniofacial researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To study what determines the arthritogenicity of bacterial cell walls, cell wall-induced arthritis in the rat was applied, using four strains of Lactobacillus. Three of the strains used proved to induce chronic arthritis in the rat; all were Lactobacillus casei. The cell wall of Lactobacillus fermentum did not induce chronic arthritis. All arthritogenic bacterial cell walls had the same peptidoglycan structure, whereas that of L. fermentum was different. Likewise, all arthritogenic cell walls were resistant to lysozyme degradation, whereas the L. fermentum cell wall was lysozyme sensitive. Muramic acid was observed in the liver, spleen, and lymph nodes in considerably larger amounts after injection of an arthritogenic L. casei cell wall than following injection of a nonarthritogenic L. fermentum cell wall. The L. casei cell wall also persisted in the tissues longer than the L. fermentum cell wall. The present results, taken together with those published previously, underline the possibility that the chemical structure of peptidoglycan is important in determining the arthritogenicity of the bacterial cell wall.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.