ReviewThe Journal of physiology2000
Regulation of neuronal function by protein trafficking: a role for the endosomal pathway.
Review in The Journal of physiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 60 citations in OpenAlex.
- Bltp1 Is Required for Survival and Normal Development and Function of the Neuromuscular Junction in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Alzheimer's Disease and Protein Kinases.Advances in experimental medicine and biology · 2021Article
- Rab GTPases and Membrane Trafficking in Neurodegeneration.Current biology : CB · 2018Review
- Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging.International journal of molecular sciences · 2017Review
- Article
- An effective plasma membrane proteomics approach for small tissue samples.Scientific reports · 2015Article
- Trafficking of ThermoTRP Channels.Membranes · 2014Review
- The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.Acta neuropathologica · 2013Article
- LRRK2 affects vesicle trafficking, neurotransmitter extracellular level and membrane receptor localization.PloS one · 2013Article
- Function suggests nano-structure: electrophysiology supports that granule membranes play dice.Journal of the Royal Society, Interface · 2012Article
- Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT.Nature neuroscience · 2011Article
- Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Estradiol effects on the dopamine transporter - protein levels, subcellular location, and function.Journal of molecular signaling · 2006Article
- The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking.Molecular biology of the cell · 2005Article
- Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.The EMBO journal · 2003Article
- Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.Molecular biology of the cell · 2003Article
- Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD.The Journal of cell biology · 2002Article
- A conserved mechanism of synaptogyrin localization.Molecular biology of the cell · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Protein trafficking plays a central role in many aspects of neuronal function, from the release of neurotransmitters by exocytosis and the recycling of synaptic vesicle proteins to the regulation of receptor signalling. Synaptic function can be significantly modified on a short time scale by alterations in the levels of receptors, ion channels and transporters both pre- and postsynaptically. In many cases, these alterations appear to be mediated by acute changes in the rates at which the proteins are endocytosed from and exocytosed to the cell surface from intracellular pools. While our current understanding of the signalling mechanisms and the intracellular pathways responsible for these acute changes is still in its infancy, intriguing details are beginning to emerge from a number of systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.