ArticleGenome research2000
A radiation hybrid map of the cat genome: implications for comparative mapping.
Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 133 citations in OpenAlex.
- Toward telomere-to-telomere cat genomes for precision medicine and conservation biology.Genome research · 2024Review
- Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution.Nature genetics · 2023Article
- Applications and efficiencies of the first cat 63K DNA array.Scientific reports · 2018Article
- Feline bone marrow-derived mesenchymal stromal cells (MSCs) show similar phenotype and functions with regards to neuronal differentiation as human MSCs.Differentiation; research in biological diversity · 2012Article
- A high-resolution map of the Nile tilapia genome: a resource for studying cichlids and other percomorphs.BMC genomics · 2012Article
- A population genetic database of cat breeds developed in coordination with a domestic cat STR multiplex.Journal of forensic sciences · 2012Article
- An integrated RH map of porcine chromosome 10.BMC genomics · 2009Article
- A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae.Genomics · 2009Article
- Article
- Generation of domestic transgenic cloned kittens using lentivirus vectors.Cloning and stem cells · 2009Article
- A first generation whole genome RH map of the river buffalo with comparison to domestic cattle.BMC genomics · 2008Article
- A high-resolution radiation hybrid map of rhesus macaque chromosome 5 identifies rearrangements in the genome assembly.Genomics · 2008Article
- Precision animal breeding.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2008Review
- A 1.5-Mb-resolution radiation hybrid map of the cat genome and comparative analysis with the canine and human genomes.Genomics · 2007Article
- An approximately 140-kb deletion associated with feline spinal muscular atrophy implies an essential LIX1 function for motor neuron survival.Genome research · 2006Article
- The Tabby cat locus maps to feline chromosome B1.Animal genetics · 2006Article
- White spotting in the domestic cat (Felis catus) maps near KIT on feline chromosome B1.Animal genetics · 2006Article
- Novel gene acquisition on carnivore Y chromosomes.PLoS genetics · 2006Article
- Development of a deer mouse whole-genome radiation hybrid panel and comparative mapping of Mus chromosome 11 loci.Mammalian genome : official journal of the International Mammalian Genome Society · 2006Article
- Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar.PLoS genetics · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ordered gene maps of mammalian species are becoming increasingly valued in assigning gene variants to function in human and animal models, as well as recapitulating the natural history of genome organization. To extend this power to the domestic cat, a radiation hybrid (RH) map of the cat was constructed integrating 424 Type I-coding genes with 176 microsatellite markers, providing coverage over all 20 feline chromosomes. Alignment of parallel RH maps of human and cat reveal 100 conserved segments ordered (CSOs) between the species, nearly three times the number observed with reciprocal chromosome painting analyses. The observed number is equivalent to theoretical predictions of the number of conserved segments to be found between cat and human, implying that 300-400 Type I gene markers is sufficient to reveal nearly all conserved segments for species that exhibit the most frequently observed "slow" rate of genome reorganization. The cat-human RH map comparisons provide a new genomic tool for comparative gene mapping in the cat and related Felidae, and provide confirmation that the cat genome organization is remarkably conserved compared with human. These data demonstrate that ordered RH-based gene maps provide the most precise assessment of comparing genomes, short of contig construction or full-sequence determination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.