ArticleBone marrow transplantation2000
Diagnostic aspects of invasive Aspergillus infections in allogeneic BMT recipients.
Article in Bone marrow transplantation, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 68 citations in OpenAlex.
- Role of biomarkers in the diagnosis of invasive aspergillosis in immunocompromised patients.Annals of clinical microbiology and antimicrobials · 2022Article
- The rise in cases of mucormycosis, candidiasis and aspergillosis amidst COVID19.Fungal biology reviews · 2021Review
- Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease: an emerging fungal disease.Current infectious disease reports · 2010Article
- Management of invasive aspergillosis in patients with COPD: rational use of voriconazole.International journal of chronic obstructive pulmonary disease · 2009Review
- Protective role of interleukin-10 promoter gene polymorphism in the pathogenesis of invasive pulmonary aspergillosis after allogeneic stem cell transplantation.Bone marrow transplantation · 2005Article
- Procalcitonin--a marker of invasive fungal infection?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2005Article
- Two years of a fungal aerobiocontamination survey in a Florentine haematology ward.European journal of epidemiology · 2004Article
- The radiological spectrum of invasive aspergillosis in children: a 10-year review.Pediatric radiology · 2003Article
- Central nervous system aspergillosis in allogeneic stem cell transplant recipients.Bone marrow transplantation · 2003Article
- Aspergillus infections in allogeneic stem cell transplant recipients: have we made any progress?Bone marrow transplantation · 2002Review
- Radiologically guided fine needle lung biopsies in the evaluation of focal pulmonary lesions in allogeneic stem cell transplant recipients.Bone marrow transplantation · 2002Article
- Treatment and outcome of invasive Aspergillus infections in allogeneic BMT recipients.Bone marrow transplantation · 2000Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate diagnostic aspects of invasive aspergillosis (IA) in allogeneic BMT recipients, the charts of 22 consecutive patients with IA transplanted in 1989-1995 were reviewed. IA was diagnosed 69-466 days (median 131 days) post BMT. In 16 patients (73%), a definite or probable diagnosis of IA was made during life. Respiratory symptoms were the presenting feature in half of the patients followed by neurological symptoms (27%). Chest X-ray revealed single or multiple nodular lesions in 10 patients; cavitation was observed in five patients. Tissue biopsy was the most common method of diagnosis (nine patients: lungs 6, liver 1, subcutaneous tissue 1, brain 1). Five IA cases were detected by nine guided fine needle lung biopsies in eight patients and without complications. Bronchoalveolar lavage was performed in 14 patients with findings suggestive of invasive pulmonary aspergillosis in eight cases. Lungs were the most common organ affected (90%) followed by central nervous system (41%). The diagnosis of IA is still difficult, and a large number of patients have advanced infection at diagnosis. Methods for early diagnosis are needed. Patients with a clinical suspicion of IA should be treated vigorously with antifungal agents during the diagnostic work-up.
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