ArticleMolecular and cellular biology2000
Nuclear export of heat shock and non-heat-shock mRNA occurs via similar pathways.
Article in Molecular and cellular biology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- Nup42 safeguards heat-induced mRNAs from nuclear condensation to support chaperone synthesis.bioRxiv : the preprint server for biology · 2026Article
- Review
- Nucleoporin FG domains facilitate mRNP remodeling at the cytoplasmic face of the nuclear pore complex.Genetics · 2014Article
- A novel RNA motif mediates the strict nuclear localization of a long noncoding RNA.Molecular and cellular biology · 2014Article
- Aiding and abetting cancer: mRNA export and the nuclear pore.Trends in cell biology · 2013Review
- Article
- The mitogen-activated protein kinase Slt2 regulates nuclear retention of non-heat shock mRNAs during heat shock-induced stress.Molecular and cellular biology · 2010Article
- 3'-end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation.The EMBO journal · 2006Article
- Characterization of the export of bulk poly(A)+ mRNA in Saccharomyces cerevisiae during the wine-making process.Applied and environmental microbiology · 2005Article
- Nonsense-mediated decay does not occur within the yeast nucleus.RNA (New York, N.Y.) · 2004Article
- Evidence that poly(A) binding protein has an evolutionarily conserved function in facilitating mRNA biogenesis and export.RNA (New York, N.Y.) · 2003Article
- Localization of nuclear retained mRNAs in Saccharomyces cerevisiae.RNA (New York, N.Y.) · 2003Article
- Rpb4p, a subunit of RNA polymerase II, mediates mRNA export during stress.Molecular biology of the cell · 2003Article
- Genome-wide analysis of nuclear mRNA export pathways in Drosophila.The EMBO journal · 2003Article
- REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export.The Journal of cell biology · 2002Article
- T7 RNA polymerase-directed transcripts are processed in yeast and link 3' end formation to mRNA nuclear export.RNA (New York, N.Y.) · 2002Article
- NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila.RNA (New York, N.Y.) · 2001Article
- Article
- Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.RNA (New York, N.Y.) · 2001Article
- Pre-mRNA processing factors are required for nuclear export.RNA (New York, N.Y.) · 2000Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Several studies of the yeast Saccharomyces cerevisiae support differential regulation of heat shock mRNA (hs mRNA) and non-hs mRNA nuclear export during stress. These include the finding that hs mRNA export at 42 degrees C is inhibited in the absence of the nucleoporinlike protein Rip1p (also called Nup42p) (C. A. Saavedra, C. M. Hammell, C. V. Heath, and C. N. Cole, Genes Dev. 11:2845-2856, 1997; F. Stutz, J. Kantor, D. Zhang, T. McCarthy, M. Neville, and M. Rosbash, Genes Dev. 11:2857-2868, 1997). However, the results reported in this paper provide little evidence for selective non-hs mRNA retention or selective hs mRNA export under heat shock conditions. First, we do not detect a block to non-hs mRNA export at 42 degrees C in a wild-type strain. Second, hs mRNA export appears to be mediated by the Ran system and several other factors previously reported to be important for general mRNA export. Third, the export of non-hs mRNA as well as hs mRNA is inhibited in the absence of Rip1p at 42 degrees C. As a corollary, we find no evidence for cis-acting hs mRNA sequences that promote transport during heat shock. Taken together, our data suggest that a shift to 42 degrees C in the absence of Rip1p impacts a late stage of transport affecting most if not all mRNA.
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