ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2000
Synapsin III: developmental expression, subcellular localization, and role in axon formation.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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Who cites it
46 citing papers in PubMed, 111 citations in OpenAlex.
- Functional KCC2 expression marks an evolutionarily conserved population of early-maturing interneurons in the perinatal cortex.Nature communications · 2025Article
- The Lack of Synapsin Alters Presynaptic Plasticity at Hippocampal Mossy Fibers in Male Mice.eNeuro · 2024Article
- Molecular and in silico analyses of SYN III gene variants in autism spectrum disorder.Irish journal of medical science · 2023Article
- A novel pathway regulates social hierarchy via lncRNA AtLAS and postsynaptic synapsin IIb.Cell research · 2020Article
- The Fragile X Mental Retardation Protein Regulates Striatal Medium Spiny Neuron Synapse Density and Dendritic Spine Morphology.Frontiers in molecular neuroscience · 2020Article
- Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells.PloS one · 2020Article
- Sparse force-bearing bridges between neighboring synaptic vesicles.Brain structure & function · 2019Article
- Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice.Oncotarget · 2018Article
- The Role of Synapsins in Neurological Disorders.Neuroscience bulletin · 2018Review
- The presynaptic machinery at the synapse of C. elegans.Invertebrate neuroscience : IN · 2018Review
- Molecular Mechanisms of Short-Term Plasticity: Role of Synapsin Phosphorylation in Augmentation and Potentiation of Spontaneous Glutamate Release.Frontiers in synaptic neuroscience · 2018Article
- Synapsins regulate brain-derived neurotrophic factor-mediated synaptic potentiation and axon elongation by acting on membrane rafts.The European journal of neuroscience · 2017Article
- Synapsins Are Downstream Players of the BDNF-Mediated Axonal Growth.Molecular neurobiology · 2017Article
- Beyond the cytoskeleton: The emerging role of organelles and membrane remodeling in the regulation of axon collateral branches.Developmental neurobiology · 2016Review
- Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development.Scientific reports · 2016Article
- Synapsin Isoforms Regulating GABA Release from Hippocampal Interneurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Synapsin III in brain development.Oncotarget · 2016Article
- Functions of synapsins in corticothalamic facilitation: important roles of synapsin I.The Journal of physiology · 2015Article
- Phosphorylation by PKA and Cdk5 Mediates the Early Effects of Synapsin III in Neuronal Morphological Maturation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Role of presynaptic phosphoprotein synapsin II in schizophrenia.World journal of psychiatry · 2015Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
We have investigated the developmental expression and subcellular localization of synapsin III, the newest member of the synapsin family, in cultured mouse hippocampal neurons. Our results indicate that synapsin III is expressed early during development, with levels peaking 7 d after plating and declining thereafter. Synapsin III is highly concentrated in growth cones. Using specific antisense oligonucleotides, we have also examined the effect of depleting synapsin III on neurite elongation and synaptogenesis. When synapsin III was suppressed immediately after plating, hippocampal neurons extended minor processes but failed to differentiate one of them as the axon. The suppression of synapsin III after axonal elongation did not affect the time course of synapse formation. The results indicate that synapsin III has a developmental time course, a subcellular localization, and a developmental function very different from those of synapsin I and synapsin II.
Indexed as
Identifiers
10804215PMC6772681W2153519347What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.