ArticleArchives of disease in childhood. Fetal and neonatal edition2000
Changes in pulmonary arterial pressure in preterm infants with chronic lung disease.
Article in Archives of disease in childhood. Fetal and neonatal edition, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants.The Cochrane database of systematic reviews · 2017Pooled it
- Hydralazine in infants with persistent hypoxemic respiratory failure.The Cochrane database of systematic reviews · 2013Pooled it
- Evidence of Echocardiographic Markers of Pulmonary Vascular Disease in Asymptomatic Infants Born Preterm at One Year of Age.The Journal of pediatrics · 2018Trial
- Current diagnosis and treatment practice for pulmonary hypertension in bronchopulmonary dysplasia-A survey study in Germany (PUsH BPD).Pulmonary circulation · 2023Article
- A scoping review of echocardiographic and lung ultrasound biomarkers of bronchopulmonary dysplasia in preterm infants.Frontiers in pediatrics · 2023Article
- PATET ratio by Doppler echocardiography: noninvasive detection of pediatric pulmonary arterial hypertension.Pediatric research · 2022Review
- The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Utility of Pulmonary Artery Acceleration Time to Estimate Systolic Pulmonary Artery Pressure in Neonates and Young Infants.Pediatric cardiology · 2020Article
- Echocardiographic Assessment of Right Ventricular Afterload in Preterm Infants: Maturational Patterns of Pulmonary Artery Acceleration Time Over the First Year of Age and Implications for Pulmonary Hypertension.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2019Article
- Echocardiographic Measurements of Right Ventricular Mechanics in Infants with Bronchopulmonary Dysplasia at 36 Weeks Postmenstrual Age.The Journal of pediatrics · 2018Article
- The mechanosensitive ion channel TRPV4 is a regulator of lung development and pulmonary vasculature stabilization.Cellular and molecular bioengineering · 2018Article
- Inflammatory Response of Pulmonary Artery Smooth Muscle Cells Exposed to Oxidative and Biophysical Stress.Inflammation · 2018Article
- Practices surrounding pulmonary hypertension and bronchopulmonary dysplasia amongst neonatologists caring for premature infants.Journal of perinatology : official journal of the California Perinatal Association · 2018Article
- Pilot observational study on haemodynamic changes after surfactant administration in preterm newborns with respiratory distress syndrome.Italian journal of pediatrics · 2014Observational
- Pulmonary Hypertension in Preterm Infants with Bronchopulmonary Dysplasia.Pediatric allergy, immunology, and pulmonology · 2014Review
- Looking beyond PPHN: the unmet challenge of chronic progressive pulmonary hypertension in the newborn.Pulmonary circulation · 2013Article
- NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol.BMC pediatrics · 2011Article
- Increased superoxide production contributes to the impaired angiogenesis of fetal pulmonary arteries with in utero pulmonary hypertension.American journal of physiology. Lung cellular and molecular physiology · 2009Article
- Optimum oxygen therapy in preterm babies.Archives of disease in childhood. Fetal and neonatal edition · 2007Review
- Echocardiographic assessment of early circulatory status in preterm infants with suspected intrauterine infection.Archives of disease in childhood. Fetal and neonatal edition · 2006Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary arterial pressure (PAP) is raised in preterm infants with respiratory distress syndrome who subsequently develop chronic lung disease. The natural history of pulmonary hypertension in infants with chronic lung disease is unknown.
objectivesTo investigate changes in PAP, assessed non-invasively using Doppler echocardiography, in infants with chronic lung disease during the 1st year of life.
methodsSerial examinations were performed in infants with chronic lung disease and healthy preterm infants. The Doppler derived acceleration time to right ventricular ejection time ratio (AT/RVET) was calculated from measurements made from the pulmonary artery velocity waveform.
resultsA total of 248 examinations were performed in 54 infants with chronic lung disease and 44 healthy preterm infants. The median AT/RVET was significantly lower in infants with chronic lung disease than in healthy preterm infants (0.31 v 0.37). AT/RVET significantly correlated with age corrected for prematurity in both infants with chronic lung disease (r = 0.67) and healthy infants (r = 0.55). There was no significant difference between the rate of change in AT/RVET between the two groups. In infants with chronic lung disease, multivariate analysis showed that AT/RVET was significantly independently associated with age and inversely with duration of supplemental oxygen treatment. Median AT/RVET was significantly lower in infants with chronic lung disease until 40-52 weeks of age corrected for prematurity.
conclusionsAlthough PAP falls with increasing age in both infants with chronic lung disease and healthy preterm infants, it remains persistently raised in infants with chronic lung disease until the end of the 1st year of life.
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