ArticleProceedings of the National Academy of Sciences of the United States of America2000
The tomato ethylene receptors NR and LeETR4 are negative regulators of ethylene response and exhibit functional compensation within a multigene family.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.
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113 citing papers in PubMed, 389 citations in OpenAlex.
- Genome-wide identification of ethylene receptor protein-coding gene families in wheat and their regulated expression during development and under multiple abiotic stresses.BMC plant biology · 2026Article
- Transcriptional control of tomato fruit development and ripening.Journal of experimental botany · 2025Review
- The 14-3-3 Protein SlTFT1 Accelerates Tomato Fruit Ripening by Binding and Stabilising YFT1 in the Ethylene Signalling Pathway.Plant biotechnology journal · 2025Article
- A comprehensive model of tomato fruit ripening regulation by the transcription factors NOR-like1, NAC-NOR, and MADS-RIN.Plant physiology · 2025Article
- Autophagy restricts tomato fruit ripening via a general role in ethylene repression.The New phytologist · 2025Article
- Ethylene response factor SlERF.D6 promotes ripening in part through transcription factors SlDEAR2 and SlTCP12.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Aminoethoxyvinylglicine and 1-Methylcyclopropene: Effects on Preharvest Drop, Fruit Maturity, Quality, and Associated Gene Expression of 'Honeycrisp' Apples in the US Mid-Atlantic.Plants (Basel, Switzerland) · 2024Article
- Exploring ethylene-related genes in Cannabis sativa: implications for sexual plasticity.Plant reproduction · 2024Article
- Key transcription factors regulate fruit ripening and metabolite accumulation in tomato.Plant physiology · 2024Article
- Integrative analysis of the methylome and transcriptome of tomato fruit (Horticulture research · 2024Article
- The Effect of Ethephon on Ethylene and Chlorophyll inInternational journal of molecular sciences · 2024Article
- Ethylene biosynthesis and signal transduction during ripening and softening in non-climacteric fruits: an overview.Frontiers in plant science · 2024Review
- Characterization of the gibberellic oxidase geneFrontiers in plant science · 2024Article
- Differential gene expression during floral transition in pineapple.Plant direct · 2023Article
- Diversity and genetic architecture of agro-morphological traits in a core collection of European traditional tomato.Journal of experimental botany · 2023Article
- Genome-wide identification and expression profiling of two-component system (TCS) genes inFrontiers in genetics · 2023Article
- Transcriptomic analysis in tomato fruit reveals divergences in genes involved in cold stress response and fruit ripening.Frontiers in plant science · 2023Article
- An overview of ethylene insensitive tomato mutants: Advantages and disadvantages for postharvest fruit shelf-life and future perspective.Frontiers in plant science · 2023Review
- Ethylene response factor ERF.D7 activates auxin response factor 2 paralogs to regulate tomato fruit ripening.Plant physiology · 2022Article
- Molecular and Genetic Events Determining the Softening of Fleshy Fruits: A Comprehensive Review.International journal of molecular sciences · 2022Review
53 more citing papers are in PubMed but not listed here.
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant hormone ethylene is involved in many developmental processes, including fruit ripening, abscission, senescence, and leaf epinasty. Tomato contains a family of ethylene receptors, designated LeETR1, LeETR2, NR, LeETR4, and LeETR5, with homology to the Arabidopsis ETR1 ethylene receptor. Transgenic plants with reduced LeETR4 gene expression display multiple symptoms of extreme ethylene sensitivity, including severe epinasty, enhanced flower senescence, and accelerated fruit ripening. Therefore, LeETR4 is a negative regulator of ethylene responses. Reduced expression of this single gene affects multiple developmental processes in tomato, whereas in Arabidopsis multiple ethylene receptors must be inactivated to increase ethylene response. Transgenic lines with reduced NR mRNA levels exhibit normal ethylene sensitivity but elevated levels of LeETR4 mRNA, indicating a functional compensation of LeETR4 for reduced NR expression. Overexpression of NR in lines with lowered LeETR4 gene expression eliminates the ethylene-sensitive phenotype, indicating that despite marked differences in structure these ethylene receptors are functionally redundant.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.