Regulatable systems: applications in gene therapy and replicating viruses.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed.

1. Regulating the expression of therapeutic transgenes by controlled intake of dietary essential amino acids.Nature biotechnology · 2016
   Article
2. Systematic transfer of prokaryotic sensors and circuits to mammalian cells.ACS synthetic biology · 2014
   Article
3. Cardiac gene therapy with SERCA2a: from bench to bedside.Journal of molecular and cellular cardiology · 2011
   Review
4. Separating lentiviral vector injection and induction of gene expression in time, does not prevent an immune response to rtTA in rats.PloS one · 2010
   Article
5. Efficient transduction of cytotoxic and anti-HIV-1 genes by a gene-regulatable lentiviral vector.Virus genes · 2009
   Article
6. Activation of transgene expression in skeletal muscle by focused ultrasound.Biochemical and biophysical research communications · 2009
   Article
7. Development of an immortalised, post-pubertal gonadotrophin-releasing hormone neuronal cell line.Journal of neuroendocrinology · 2008
   Article
8. Molecular engineering of viral gene delivery vehicles.Annual review of biomedical engineering · 2008
   Review
9. Synthetic tetracycline-inducible regulatory networks: computer-aided design of dynamic phenotypes.BMC systems biology · 2007
   Article
10. New strategies for cardiovascular gene therapy: regulatable pre-emptive expression of pro-angiogenic and antioxidant genes.Cell biochemistry and biophysics · 2006
    Review
11. Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter.Nucleic acids research · 2005
    Article
12. Liver-specific expression of interferon gamma following adenoviral gene transfer controls hepatitis B virus replication in mice.Gene therapy · 2005
    Article
13. New complex Ad vectors incorporating both rtTA and tTS deliver tightly regulated transgene expression both in vitro and in vivo.Gene therapy · 2005
    Article
14. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference.Journal of virology · 2003
    Article
15. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.Journal of virology · 2002
    Article
16. Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.Gene therapy · 2002
    Article
17. Endogenous regulation of a therapeutic transgene restores homeostasis in arthritic joints.The Journal of clinical investigation · 2002
    Article
18. Immunomodulation of cancer: potential use of selectively replicating agents.The Journal of clinical investigation · 2000
    Review
19. Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer.The Journal of clinical investigation · 2000
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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