ArticleJournal of clinical microbiology2000
Direct molecular typing of Borrelia burgdorferi sensu lato species in synovial samples from patients with lyme arthritis.
Article in Journal of clinical microbiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 87 citations in OpenAlex.
- Lyme borreliosis.Nature reviews. Disease primers · 2026Review
- Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024Review
- Molecular and Serological Identification ofPathogens (Basel, Switzerland) · 2023Article
- Lyme arthritis in Western Europe: a multicentre retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Observational
- Gap Analysis of the Habitat Interface of Ticks and Wildlife in Mexico.Pathogens (Basel, Switzerland) · 2021Review
- Review
- Multilocus sequence typing of clinical Borreliella afzelii strains: population structure and differential ability to disseminate in humans.Parasites & vectors · 2018Article
- Characterization of the inner membrane protein BB0173 from Borrelia burgdorferi.BMC microbiology · 2017Article
- Oligoarthritis caused by Borrelia bavariensis, Austria, 2014.Emerging infectious diseases · 2015Review
- Prevalence of Borrelia burgdorferi-infected ticks from wildlife hosts, a response to Norris et al.Parasites & vectors · 2015Article
- Implications of climate change on the distribution of the tick vector Ixodes scapularis and risk for Lyme disease in the Texas-Mexico transboundary region.Parasites & vectors · 2014Article
- Pathogenic Landscape of Transboundary Zoonotic Diseases in the Mexico-US Border Along the Rio Grande.Frontiers in public health · 2014Review
- BB0172, a Borrelia burgdorferi outer membrane protein that binds integrin α3β1.Journal of bacteriology · 2013Article
- Borrelia carolinensis sp. nov., a new (14th) member of the Borrelia burgdorferi Sensu Lato complex from the southeastern region of the United States.Journal of clinical microbiology · 2009Article
- MyD88 negatively controls hypergammaglobulinemia with autoantibody production during bacterial infection.Infection and immunity · 2008Article
- Borrelia burgdorferi infection and cutaneous Lyme disease, Mexico.Emerging infectious diseases · 2007Article
- Lyme meningoradiculitis: prospective evaluation of biological diagnosis methods.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2007Article
- Antibiotic treatment of Lyme borreliosis: what is the evidence?Annals of the rheumatic diseases · 2005Review
- Review
- Prevalence of Borrelia burgdorferi species and identification of Borrelia valaisiana in questing Ixodes ricinus in the Lyon region of France as determined by polymerase chain reaction-restriction fragment length polymorphism.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2003Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since Lyme arthritis was first described in the United States, it has now been reported in many countries of Europe. However, very few strains of the causative bacterium, Borrelia burgdorferi, have been isolated from synovial samples. For this reason, different molecular direct typing methods were developed recently to assess which species could be involved in Lyme arthritis in Europe. We developed a simple oligonucleotide typing method with PCR fragments from the flagellin gene of B. burgdorferi sensu lato, which is able to differentiate seven different Borrelia species. Among 10 consecutive PCR-positive patients with Lyme arthritis from the northeastern France, two species were identified in synovial samples: B. burgdorferi sensu stricto in 9 cases and B. garinii in 1 case. Conversely, all B. burgdorferi sensu lato species detected in 10 consecutive PCR-positive biopsies from a second set of patients with erythema migrans from the same geographical area were identified as either B. afzelii or B. garinii (P < 0.001). These results indicate that B. burgdorferi sensu stricto is the principal but not the only Borrelia species involved in Lyme arthritis in northeastern France.
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