ReviewPostgraduate medical journal2000
Role of smoking in inflammatory bowel disease: implications for therapy.
Review in Postgraduate medical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Dietary intake of fish, n-3 polyunsaturated fatty acids, and risk of inflammatory bowel disease: a systematic review and meta-analysis of observational studies.European journal of nutrition · 2020Pooled it
- Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.Gastroenterology · 2017Pooled it
- The effect of smoking in inflammatory bowel disease outcomes.Frontiers in gastroenterology (Lausanne, Switzerland) · 2024Article
- Review
- The association of smoking and socioeconomic status on cutaneous melanoma: a population-based, data-linkage, case-control study.The British journal of dermatology · 2020Article
- Article
- Exploring the Effects of Cigarette Smoking on Inflammatory Bowel Disease Using Mendelian Randomization.Crohn's & colitis 360 · 2020Article
- Selective JAKinibs: Prospects in Inflammatory and Autoimmune Diseases.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2019Review
- Current smoking habits in British IBD patients in the age of e-cigarettes.BMJ open gastroenterology · 2019Article
- Anti-Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease.JAMA neurology · 2018Article
- The intestinal barrier: a fundamental role in health and disease.Expert review of gastroenterology & hepatology · 2017Review
- Article
- Tracheal and bronchial involvement in colitis ulcerosa - a colo-bronchitic syndrome? A case report and some additional considerations.German medical science : GMS e-journal · 2015Review
- Inflammatory bowel diseases and human reproduction: a comprehensive evidence-based review.World journal of gastroenterology · 2014Review
- Impact of smoking on disease phenotype and postoperative outcomes for Crohn's disease patients undergoing surgery.Langenbeck's archives of surgery · 2013Article
- Nicotinic acetylcholine receptor expression and susceptibility to cholinergic immunomodulation in human monocytes of smoking individuals.Neuroimmunomodulation · 2012Article
- Laparoscopic subtotal colectomy for medically refractory ulcerative colitis: the time has come.Surgical endoscopy · 2010Article
- Article
- Current concept of pathophysiological understanding and natural course of ulcerative colitis.Langenbeck's archives of surgery · 2004Review
- Nicotine conjugate vaccine: is there a right to a smoking future?Journal of medical ethics · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between smoking and inflammatory bowel disease is now firmly established but remains a source of confusion among both patients and doctors. It is negatively associated with ulcerative colitis but positively associated with Crohn's disease. In addition, it has opposite influences on the clinical course of the two conditions with benefit in ulcerative colitis but a detrimental effect in Crohn's disease. These differences have been the subject of much interest and scrutiny with the hope that they may offer some insight into the pathogenesis of the two conditions and possibly lead to alternative therapeutic options. Nicotine is probably the principal active ingredient in smoking responsible for the association; trials have shown it to be of some benefit in ulcerative colitis, but further research is required to establish its therapeutic role, and the relevant mechanisms responsible for its action. In this article, we review the role of smoking in inflammatory bowel disease and its implication for therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.