Evidence map›Paper›PMID 10775277›Full record

ReviewPostgraduate medical journal2000

Impact of HIV infection on tuberculosis.

A Zumla, P Malon, J Henderson, J M Grange

Open access · bronzeAbstract readReview
In one paragraph

Review in Postgraduate medical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 171 citations in OpenAlex.

  1. Pooled it
  2. Nutritional supplements for people being treated for active tuberculosis.The Cochrane database of systematic reviews · 2016
    Pooled it
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  18. Influence of patients' living conditions on tuberculosis treatment outcomes in a South African health sub-district.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

A ZumlaCentre for Infectious Diseases, University College London, Royal Free and University College Medical School, Windeyer Institute of Medical Sciences, Room G41, 46 Cleveland Street, London W1P 6DB, UK. a.zumla@ucl.ac.uk
P Malon
J Henderson
J M Grange
University College Hospital · GBThe Royal Free Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis is increasing in prevalence in many countries and is now the leading infectious cause of death world wide, being responsible for three million deaths annually. Infection with HIV, likewise increasing in prevalence, has emerged as the most important predisposing factor for developing overt tuberculosis in people co-infected with Mycobacterium tuberculosis. Owing to the widespread geographical overlap of these two infections, it is estimated that in 1999, HIV related tuberculosis will reach one million cases and will cause 30% of the expected 2.5 million AIDS related deaths. Tuberculosis in HIV infected individuals may have unusual clinical features and can cause diagnostic difficulties. Despite the effectiveness of modern short course treatment, the mortality of HIV related tuberculosis during and after treatment remains high, and this may be due to other HIV related infections. The "cursed duet" of infection with both HIV and M tuberculosis is generating a threat to human health of unparalleled proportions which, if not taken seriously by health workers and decision makers, could become totally unmanageable.

Indexed as

AIDS-Related Opportunistic InfectionsAntitubercular AgentsChildChild, PreschoolDisease SusceptibilityGlobal HealthHIVHumansPrevalenceSerologic TestsTuberculosisAntitubercular Agents

Identifiers

PMID10775277
PMCPMC1741590
OpenAlexW2103660106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.