ArticleNucleic acids research2000
DNA repair in a yeast origin of replication: contributions of photolyase and nucleotide excision repair.
Article in Nucleic acids research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Photoreactivation Activities of Rad5, Rad16A and Rad16B HelpJournal of fungi (Basel, Switzerland) · 2024Article
- Divergent roles of Rad4 and Rad23 homologs inApplied and environmental microbiology · 2023Article
- Co-Regulatory Roles of WC1 and WC2 in Asexual Development and Photoreactivation ofJournal of fungi (Basel, Switzerland) · 2023Article
- Comparative Roles of Rad4A and Rad4B in Photoprotection ofJournal of fungi (Basel, Switzerland) · 2023Article
- Rad1 and Rad10 Tied to Photolyase Regulators Protect Insecticidal Fungal Cells from Solar UV Damage by Photoreactivation.Journal of fungi (Basel, Switzerland) · 2022Article
- A Global Analysis of Photoreceptor-Mediated Transcriptional Changes Reveals the Intricate Relationship Between Central Metabolism and DNA Repair in the Filamentous FungusFrontiers in microbiology · 2021Article
- Photoprotective Role of Photolyase-Interacting RAD23 and Its Pleiotropic Effect on the Insect-Pathogenic Fungus Beauveria bassiana.Applied and environmental microbiology · 2020Article
- Two Photolyases Repair Distinct DNA Lesions and Reactivate UVB-Inactivated Conidia of an Insect Mycopathogen under Visible Light.Applied and environmental microbiology · 2019Article
- RNA-seq analysis of the transcriptional response to blue and red light in the extremophilic red alga, Cyanidioschyzon merolae.Functional & integrative genomics · 2016Article
- The somatic autosomal mutation matrix in cancer genomes.Human genetics · 2015Article
- Rapid accessibility of nucleosomal DNA in yeast on a second time scale.The EMBO journal · 2006Article
- A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome.Genome research · 2006Article
- Kinetochores prevent repair of UV damage in Saccharomyces cerevisiae centromeres.Molecular and cellular biology · 2004Article
- Photoreactivation of UV-induced cyclobutane pyrimidine dimers in the MFA2 gene of Saccharomyces cerevisiae.Nucleic acids research · 2002Article
- Poly(dA.dT) sequences exist as rigid DNA structures in nucleosome-free yeast promoters in vivo.Nucleic acids research · 2000Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA damage formation and repair are tightly linked to protein-DNA interactions in chromatin. We have used minichromosomes in yeast as chromatin substrates in vivo to investigate how nucleotide excision repair (NER) and repair by DNA-photolyase (photoreactivation) remove pyrimidine dimers from an origin of replication ( ARS1 ). The ARS1 region is nuclease sensitive and flanked by nucleosomes on both sides. Photoreactivation was generally faster than NER at all sites. Site-specific heterogeneity of repair was observed for both pathways. This heterogeneity was different for NER and photoreactivation and it was altered in a minichromosome where ARS1 was transcribed. The results indicate distinct inter-actions of the repair systems with protein complexes bound in the ARS region (ORC, Abf1) and a predominant role of photolyase in CPD repair of an origin of replication.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.