Evidence map›Paper›PMID 10770785›Full record

ArticleAntimicrobial agents and chemotherapy2000

In vitro activity of telithromycin (HMR3647), a new ketolide, against clinical isolates of Mycoplasma pneumoniae in Japan.

T Yamaguchi, Y Hirakata, K Izumikawa, Y Miyazaki, S Maesaki, K Tomono, Y Yamada, S Kamihira, S Kohno

Open access · greenAbstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Antimicrobial agents and chemotherapy · 2017
    Article
  3. Transport of Azithromycin into Extravascular Space in Rats.Antimicrobial agents and chemotherapy · 2016
    Article
  4. Mycoplasma pneumonia: Clinical features and management.Lung India : official organ of Indian Chest Society · 2010
    Article
  5. Article
  6. Article
  7. Review
  8. Telithromycin.Drugs · 2004
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Telithromycin.Drugs · 2001
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

T YamaguchiDepartment of Laboratory Medicine, Nagasaki University School of Medicine, Nagasaki 852-8501, Japan. toshi-ngs@umin.ac.jp
Y Hirakata
K Izumikawa
Y Miyazaki
S Maesaki
K Tomono
Y Yamada
S Kamihira
S Kohno
Nagasaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vitro activity of telithromycin (HMR3647), a new ketolide, against Mycoplasma pneumoniae was determined by the broth microdilution test using 41 clinical isolates obtained in Japan, as compared with those of five macrolides (erythromycin, clarithromycin, roxithromycin, azithromycin, and josamycin), minocycline, and levofloxacin. Telithromycin was less potent than azithromycin, but it was more active than four other macrolides, minocycline, and levofloxacin; its MICs at which 50 and 90% of the isolates tested were inhibited were both 0.00097 microg/ml, justifying clinical studies to determine its efficacy for treatment of M. pneumoniae.

Indexed as

KetolidesMacrolidesAnti-Bacterial AgentsHumansJapanMicrobial Sensitivity TestsMycoplasma pneumoniaeAnti-Bacterial AgentsKetolidesMacrolidestelithromycin

Identifiers

PMID10770785
PMCPMC89878
OpenAlexW2100867931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.