ArticleAntimicrobial agents and chemotherapy2000
Comparative killing rates of fluoroquinolones and cell wall-active agents.
Article in Antimicrobial agents and chemotherapy, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Successful fluoroquinolone-based salvage therapy in the conservative management of refractory infective endocarditis caused byOxford medical case reports · 2025Article
- Evaluation the kill rate and mutant selection window of danofloxacin against Actinobacillus pleuropneumoniae in a peristaltic pump model.BMC veterinary research · 2024Article
- PK-PD integration of enrofloxacin and cefquinome alone and in combination againstFrontiers in pharmacology · 2023Article
- Probing the Mechanism of LAL-32, a Gold Nanoparticle-Based Antibiotic Discovered through Small Molecule Variable Ligand Display.Bioconjugate chemistry · 2017Article
- Population Density Modulates Drug Inhibition and Gives Rise to Potential Bistability of Treatment Outcomes for Bacterial Infections.PLoS computational biology · 2016Article
- Modeling the growth dynamics of multiple Escherichia coli strains in the pig intestine following intramuscular ampicillin treatment.BMC microbiology · 2016Article
- Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli.Acta veterinaria Scandinavica · 2015Article
- Translating slow-binding inhibition kinetics into cellular and in vivo effects.Nature chemical biology · 2015Article
- The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins.Antimicrobial agents and chemotherapy · 2010Article
- Mechanism-based pharmacodynamic models of fluoroquinolone resistance in Staphylococcus aureus.Antimicrobial agents and chemotherapy · 2006Article
- Phenotypic tolerance: antibiotic enrichment of noninherited resistance in bacterial populations.Antimicrobial agents and chemotherapy · 2005Article
- Pharmacodynamic functions: a multiparameter approach to the design of antibiotic treatment regimens.Antimicrobial agents and chemotherapy · 2004Article
- Synergistic activities of gatifloxacin in combination with other antimicrobial agents against Pseudomonas aeruginosa and related species.Antimicrobial agents and chemotherapy · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Killing rates of fluoroquinolones, beta-lactams, and vancomycin were compared against Enterobacteriaceae, Staphylococcus aureus, pneumococci, streptococci, and Enterococcus faecalis. The times required for fluoroquinolones to decrease viability by 3 log(10) were 1.5 h for Enterobacteriaceae, 4 to 6 h for staphylococci, and >/=6 h for streptococci and enterococci. Thus, the rate of killing by fluoroquinolones is organism group dependent; overall, they killed more rapidly than beta-lactams and vancomycin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.