ArticleInfection and immunity2000
Increased levels of soluble Fas ligand in serum in Plasmodium falciparum malaria.
Article in Infection and immunity, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Changes in total and differential leukocyte counts during the clinically silent liver phase in a controlled human malaria infection in malaria-naïve Dutch volunteers.Malaria journal · 2017Trial
- Alteration of Fas and Fas ligand expression during human visceral leishmaniasis.Clinical and experimental immunology · 2002Trial
- Overview of the host immune response toJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Review
- SARS-CoV-2-associated lymphopenia: possible mechanisms and the role of CD147.Cell communication and signaling : CCS · 2024Review
- Association of apoptosis-related variants to malaria infection and parasite density in individuals from the Brazilian Amazon.Malaria journal · 2023Article
- Immunogenomic profile at baseline predicts host susceptibility to clinical malaria.Frontiers in immunology · 2023Article
- Memory B cell diversity: insights for optimized vaccine design.Trends in immunology · 2022Review
- Review
- Cytokine Profile Distinguishes Children With Plasmodium falciparum Malaria From Those With Bacterial Blood Stream Infections.The Journal of infectious diseases · 2020Article
- A novel in vitro model reveals distinctive modulatory roles of Plasmodium falciparum and Plasmodium vivax on naïve cell-mediated immunity.Malaria journal · 2017Article
- Parasite and the Circulating Pool- Characterisation of Leukocyte Number and Morphology in Malaria.Journal of clinical and diagnostic research : JCDR · 2016Article
- Induction of Inhibitory Receptors on T Cells During Plasmodium vivax Malaria Impairs Cytokine Production.The Journal of infectious diseases · 2015Article
- Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria.Clinical and vaccine immunology : CVI · 2015Article
- Proapoptotic CD95L levels in normal human serum and sera of breast cancer patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- CD4+ T cells apoptosis in Plasmodium vivax infection is mediated by activation of both intrinsic and extrinsic pathways.Malaria journal · 2015Article
- Leukogram Profile and Clinical Status in vivax and falciparum Malaria Patients from Colombia.Journal of tropical medicine · 2015Article
- Human Gene Expression in Uncomplicated Plasmodium falciparum Malaria.Journal of immunology research · 2015Article
- Impairment of T cell function in parasitic infections.PLoS neglected tropical diseases · 2014Review
- Predictive value of lymphocytopenia and the neutrophil-lymphocyte count ratio for severe imported malaria.Malaria journal · 2013Article
- How Reliable Are Hematological Parameters in Predicting UncomplicatedISRN tropical medicine · 2013Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Levels of soluble Fas ligand (sFasL) in serum were elevated in patients with Plasmodium falciparum malaria and showed a significant decline during disease course. sFasL levels that were elevated before antimalarial treatment began correlated significantly with depressed total lymphocyte and T-cell counts. These data suggest that Fas-induced apoptosis might play a role in malaria-associated lymphopenia.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.