Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

17 citing papers in PubMed, 77 citations in OpenAlex.

1. Complement factor H in AMD: Bridging genetic associations and pathobiology.Progress in retinal and eye research · 2018
   Review
2. The Genetics of Ultra-Rare Renal Disease.Journal of pediatric genetics · 2016
   Review
3. Eculizumab in neonatal hemolytic uremic syndrome with homozygous factor H deficiency.Pediatric nephrology (Berlin, Germany) · 2014
   Article
4. Current treatment of atypical hemolytic uremic syndrome.Intractable & rare diseases research · 2014
   Review
5. DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN.Journal of the American Society of Nephrology : JASN · 2013
   Article
6. Structural basis for engagement by complement factor H of C3b on a self surface.Nature structural & molecular biology · 2011
   Article
7. Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities.The Journal of biological chemistry · 2011
   Article
8. Complement control protein factor H: the good, the bad, and the inadequate.Molecular immunology · 2010
   Review
9. The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module.Journal of molecular biology · 2010
   Article
10. Serum cystatin C level, kidney disease markers, and incidence of age-related macular degeneration: the Beaver Dam Eye Study.Archives of ophthalmology (Chicago, Ill. : 1960) · 2009
    Article
11. Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals.Clinical and experimental immunology · 2008
    Review
12. Complement factor H: using atomic resolution structure to illuminate disease mechanisms.Advances in experimental medicine and biology · 2008
    Review
13. Pathogenesis of thrombotic microangiopathies.Annual review of pathology · 2008
    Review
14. Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome.The Journal of clinical investigation · 2003
    Article
15. Structural and functional characterization of factor H mutations associated with atypical hemolytic uremic syndrome.American journal of human genetics · 2002
    Article
16. Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition.American journal of human genetics · 2001
    Article
17. Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome.American journal of human genetics · 2001
    Article

Corrections and comments

• Comment on
  Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome.1999

Authors and funding

5 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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