ArticleThe Plant cell2000
Arabidopsis RTM2 gene is necessary for specific restriction of tobacco etch virus and encodes an unusual small heat shock-like protein.
Article in The Plant cell, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 175 citations in OpenAlex.
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- Regulatory DNA Sequences Controlling Gene Expression in Leaf Phloem Cells.Methods in molecular biology (Clifton, N.J.) · 2026Review
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- Orsay virus infection increasesBiology letters · 2024Article
- Engineering Resistance Against Viruses in Field Crops Using CRISPR- Cas9.Current genomics · 2021Review
- Characterization of Local and Systemic Impact of Whitefly (International journal of molecular sciences · 2020Article
- Natural resistance to Potato virus Y in Solanum tuberosum Group Phureja.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
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- Soybean antiviral immunity conferred by dsRNase targets the viral replication complex.Nature communications · 2019Article
- The Tug-of-War between Plants and Viruses: Great Progress and Many Remaining Questions.Viruses · 2019Review
- The Plant Noncanonical Antiviral Resistance Protein JAX1 Inhibits Potexviral Replication by Targeting the Viral RNA-Dependent RNA Polymerase.Journal of virology · 2019Article
- Genetic dissection of Sharka disease tolerance in peach (P. persica L. Batsch).BMC plant biology · 2017Article
- SIEVE ELEMENT-LINING CHAPERONE1 Restricts Aphid Feeding on Arabidopsis during Heat Stress.The Plant cell · 2017Article
- Plant immunity against viruses: antiviral immune receptors in focus.Annals of botany · 2017Review
- The transcriptomics of an experimentally evolved plant-virus interaction.Scientific reports · 2016Article
- Identification of haplotypes at the Rsv4 genomic region in soybean associated with durable resistance to soybean mosaic virus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Immune Receptors and Co-receptors in Antiviral Innate Immunity in Plants.Frontiers in microbiology · 2016Review
- The α-Crystallin Domain Containing Genes: Identification, Phylogeny and Expression Profiling in Abiotic Stress, Phytohormone Response and Development in Tomato (Solanum lycopersicum).Frontiers in plant science · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Arabidopsis plants have a system to specifically restrict the long-distance movement of tobacco etch potyvirus (TEV) without involving either hypersensitive cell death or systemic acquired resistance. At least two dominant genes, RTM1 and RTM2, are necessary for this restriction. Through a series of coinfection experiments with heterologous viruses, the RTM1/RTM2-mediated restriction was shown to be highly specific for TEV. The RTM2 gene was isolated by a map-based cloning strategy. Isolation of RTM2 was confirmed by transgenic complementation and sequence analysis of wild-type and mutant alleles. The RTM2 gene product is a multidomain protein containing an N-terminal region with high similarity to plant small heat shock proteins (HSPs). Phylogenetic analysis revealed that the RTM2 small HSP-like domain is evolutionarily distinct from each of the five known classes of plant small HSPs. Unlike most other plant genes encoding small HSPs, expression of the RTM2 gene was not induced by high temperature and did not contribute to thermotolerance of seedlings. The RTM2 gene product was also shown to contain a large C-terminal region with multiple repeating sequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.