ArticleThe Plant cell2000
Heat shock protein 101 plays a crucial role in thermotolerance in Arabidopsis.
Article in The Plant cell, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 263 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
263 citing papers in PubMed, 1 synthesis or guideline pooled it, 708 citations in OpenAlex.
- Pearl millet response to drought: A review.Frontiers in plant science · 2023Pooled it
- Aspects of plant intelligence (ii).Plant signaling & behavior · 2026Review
- SRF6, a heat-inducible receptor-like kinase, regulates thermotolerance in Arabidopsis thaliana.Plant cell reports · 2026Article
- Trans-2-hexenal priming supports HSFA2-independent thermotolerance in Arabidopsis thaliana.Journal of plant research · 2026Article
- Gene Families, Structural and Functional Contexts Shape Protein Thermostability and Paralog Divergence inPlants (Basel, Switzerland) · 2026Article
- The transcriptional cascade CiERF023Horticulture research · 2026Article
- Adaptive response to long-term high temperatures during the reproductive development in Arabidopsis thaliana.Planta · 2026Article
- Article
- Mixed-class J-domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly.FEBS letters · 2026Article
- Article
- Natural variation uncouples HSFA2 induction from volatile-induced thermotolerance in Arabidopsis thaliana.Plant molecular biology · 2026Article
- Decoding core molecular mechanisms of heat-stress tolerance in Brassica napus using transcriptomics and machine learning.Plant cell reports · 2026Article
- Impact of pectin methylesterase on endophyte communities and pathogen resistance in Arabidopsis under heat stress.World journal of microbiology & biotechnology · 2026Article
- Molecular mechanisms and breeding strategies for heat tolerance in vegetable crops under global warming.Horticulture research · 2026Article
- Membrane stability under heat stress: molecular signaling, lipid remodeling, and defense mechanisms in plants.Plant cell reports · 2026Review
- In silico characterization, evolutionary analysis, and structural modeling of HSP70 gene family in carrot (Daucus Carota L.).BMC plant biology · 2026Article
- Transcriptomic analysis of reduced thermotolerance inFrontiers in plant science · 2026Article
- Review
- Analysis of plant gene family heat shock protein 100 (HSP100) and its orthologs in Eukarya reveals sites of divergent evolution and insights into endosymbiotic origins of chloroplasts.Plant signaling & behavior · 2025Article
- Deciphering the genetic basis of chlorophyll fluorescence parameters and vegetation indices under heat stress in blueberry.BMC plant biology · 2025Article
203 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants are sessile organisms, and their ability to adapt to stress is crucial for survival in natural environments. Many observations suggest a relationship between stress tolerance and heat shock proteins (HSPs) in plants, but the roles of individual HSPs are poorly characterized. We report that transgenic Arabidopsis plants expressing less than usual amounts of HSP101, a result of either antisense inhibition or cosuppression, grew at normal rates but had a severely diminished capacity to acquire heat tolerance after mild conditioning pretreatments. The naturally high tolerance of germinating seeds, which express HSP101 as a result of developmental regulation, was also profoundly decreased. Conversely, plants constitutively expressing HSP101 tolerated sudden shifts to extreme temperatures better than did vector controls. We conclude that HSP101 plays a pivotal role in heat tolerance in Arabidopsis. Given the high evolutionary conservation of this protein and the fact that altering HSP101 expression had no detrimental effects on normal growth or development, one should be able to manipulate the stress tolerance of other plants by altering the expression of this protein.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.