Evidence map›Paper›PMID 10757803›Full record

ArticleMolecular and cellular biology2000

Structure of a polycomb response element and in vitro binding of polycomb group complexes containing GAGA factor.

B Horard, C Tatout, S Poux, V Pirrotta

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 214 citations in OpenAlex.

  1. Article
  2. Article
  3. Polycomb Recruiters Inside and Outside of the Repressed Domains.International journal of molecular sciences · 2023
    Review
  4. The role of O-GlcNAcylation in development.Development (Cambridge, England) · 2023
    Article
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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

B HorardDepartment of Zoology, University of Geneva, CH1211 Geneva, Switzerland.
C Tatout
S Poux
V Pirrotta
University of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycomb response elements (PREs) are regulatory sites that mediate the silencing of homeotic and other genes. The bxd PRE region from the Drosophila Ultrabithorax gene can be subdivided into subfragments of 100 to 200 bp that retain different degrees of PRE activity in vivo. In vitro, embryonic nuclear extracts form complexes containing Polycomb group (PcG) proteins with these fragments. PcG binding to some fragments is dependent on consensus sequences for the GAGA factor. Other fragments lack GAGA binding sites but can still bind PcG complexes in vitro. We show that the GAGA factor is a component of at least some types of PcG complexes and may participate in the assembly of PcG complexes at PREs.

Indexed as

Drosophila ProteinsAnimalsAnimals, Genetically ModifiedBase SequenceBinding, CompetitiveBinding SitesDNA-Binding ProteinsDNA Transposable ElementsDrosophilaGene Expression Regulation, DevelopmentalHomeodomain ProteinsHSP70 Heat-Shock ProteinsInsect ProteinsModels, GeneticMolecular Sequence DataPolycomb Repressive Complex 1DNA-Binding ProteinsDNA Transposable ElementsDrosophila ProteinsHomeodomain ProteinsHSP70 Heat-Shock ProteinsInsect ProteinsPc protein, DrosophilaPolycomb Repressive Complex 1Transcription FactorsTrl protein, DrosophilaUbx protein, Drosophila

Identifiers

PMID10757803
PMCPMC85613
OpenAlexW1980132133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.