Evidence map›Paper›PMID 10756057›Full record

ArticleJournal of virology2000

Retroviral vector targeting to human immunodeficiency virus type 1-infected cells by receptor pseudotyping.

N V Somia, H Miyoshi, M J Schmitt, I M Verma

Abstract read
In one paragraph

Article in Journal of virology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Lentiviral vectors for immune cells targeting.Immunopharmacology and immunotoxicology · 2010
    Review
  8. Molecular engineering of viral gene delivery vehicles.Annual review of biomedical engineering · 2008
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Lipid rafts and pseudotyping.Journal of virology · 2001
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

N V SomiaLaboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.
H Miyoshi
M J Schmitt
I M Verma
Salk Institute for Biological Studies · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the generation of retroviral vectors based on Moloney murine leukemia virus that specifically transduce cells infected with T-cell-tropic human immunodeficiency virus type 1 (HIV-1). This vector was pseudotyped with T-cell-tropic HIV-1 receptors CD4 and CXCR4. We demonstrate that transduction is contingent upon HIV-1 gp120 and gp41 expression.

Indexed as

Genetic VectorsMoloney murine leukemia virusAnimalsCD4 AntigensGene TargetingHeLa CellsHIV-1HIV Envelope Protein gp120HIV Envelope Protein gp41HumansMiceReceptors, CXCR4CD4 AntigensHIV Envelope Protein gp120HIV Envelope Protein gp41Receptors, CXCR4

Identifiers

PMID10756057
PMCPMC111959
OpenAlexW2025208624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.