ArticleJournal of virology2000
Frequent homologous recombination events between molecules of one RNA component in a multipartite RNA virus.
Article in Journal of virology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 76 citations in OpenAlex.
- A review of the recombination events, mechanisms and consequences of Coxsackievirus A6.Infectious medicine · 2024Review
- Transmission of Diverse Variants of Strawberry Viruses Is Governed by a Vector Species.Viruses · 2022Article
- Generated Randomly and Selected Functionally? The Nature of Enterovirus Recombination.Viruses · 2022Article
- Imprecise recombinant viruses evolve via a fitness-driven, iterative process of polymerase template-switching events.PLoS pathogens · 2021Article
- Impact of Cultivated Hosts on the Recombination ofJournal of virology · 2019Article
- An ImprovedPlant physiology · 2018Article
- Viral metagenomics of aphids present in bean and maize plots on mixed-use farms in Kenya reveals the presence of three dicistroviruses including a novel Big Sioux River virus-like dicistrovirus.Virology journal · 2017Article
- Identification of three new isolates of Tomato spotted wilt virus from different hosts in China: molecular diversity, phylogenetic and recombination analyses.Virology journal · 2016Article
- Mutation and recombination frequencies reveal a biological contrast within strains of Cucumber mosaic virus.Journal of virology · 2015Article
- Ecosystem simplification, biodiversity loss and plant virus emergence.Current opinion in virology · 2015Review
- Co-infection with two strains of Brome mosaic bromovirus reveals common RNA recombination sites in different hosts.Virus evolution · 2015Article
- Genetic Diversity of a Natural Population of Apple stem pitting virus Isolated from Apple in Korea.The plant pathology journal · 2014Article
- Application of motif-based tools on evolutionary analysis of multipartite single-stranded DNA viruses.PloS one · 2013Article
- Article
- Distribution of the phenotypic effects of random homologous recombination between two virus species.PLoS pathogens · 2011Article
- Recombination of 5' subgenomic RNA3a with genomic RNA3 of Brome mosaic bromovirus in vitro and in vivo.Virology · 2011Article
- Evidence that the linker between the methyltransferase and helicase domains of potato virus X replicase is involved in homologous RNA recombination.Journal of virology · 2009Article
- In vivo packaging of brome mosaic virus RNA3, but not RNAs 1 and 2, is dependent on a cis-acting 3' tRNA-like structure.Journal of virology · 2007Article
- Characterization of a novel 5' subgenomic RNA3a derived from RNA3 of Brome mosaic bromovirus.Journal of virology · 2006Article
- A universal BMV-based RNA recombination system--how to search for general rules in RNA recombination.Nucleic acids research · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Brome mosaic bromovirus (BMV), a tripartite plus-sense RNA virus, has been used as a model system to study homologous RNA recombination among molecules of the same RNA component. Pairs of BMV RNA3 variants carrying marker mutations at different locations were coinoculated on a local lesion host, and the progeny RNA3 in a large number of lesions was analyzed. The majority of doubly infected lesions accumulated the RNA3 recombinants. The distribution of the recombinant types was relatively even, indicating that both RNA3 counterparts could serve as donor or as acceptor molecules. The frequency of crossovers between one pair of RNA3 variants, which possessed closely located markers, was similar to that of another pair of RNA3 variants with more distant markers, suggesting the existence of an internal recombination hot spot. The majority of crossovers were precise, but some recombinants had minor sequence modifications, possibly marking the sites of imprecise homologous crossovers. Our results suggest discontinuous RNA replication, with the replicase changing among the homologous RNA templates and generating RNA diversity. This approach can be easily extended to other RNA viruses for identification of homologous recombination hot spots.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.