Evidence map›Paper›PMID 10748868›Full record

ArticleMolecular pathology : MP1999

HHV-8 (KSHV) is not associated with bacillary angiomatosis.

S J Nayler, U Allard, L Taylor, K Cooper

Open access · bronzeAbstract read
In one paragraph

Article in Molecular pathology : MP, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 21 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

S J NaylerDepartment of Anatomical Pathology, School of Pathology, South African Institute for Medical Research, Johannesburg, South Africa. simonn@mail.saimr.wits.ac.za
U Allard
L Taylor
K Cooper
South African Institute for Medical Research · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsBacillary angiomatosis is a rare pseudoneoplastic angioproliferative lesion occurring in patients with AIDS. This condition has been associated with Bartonella henselae and Bartonella quintana infections. Human herpesvirus 8 (HHV-8) is thought to be the causative agent of Kaposi's sarcoma, a vasoproliferative neoplasm, also commonly found in patients with AIDS. The presence of HHV-8 in a cohort of patients with bacillary angiomatosis was investigated.

methodsEight cutaneous cases of biopsy confirmed bacillary angiomatosis were assessed for HHV-8 using standard solution phase polymerase chain reaction (PCR).

resultsNo case of bacillary angiomatosis harboured HHV-8 DNA.

conclusionsHHV-8 was not demonstrated in the lesions of bacillary angiomatosis and therefore does not appear to play a role in the pathogenesis of this pseudoneoplastic angioproliferative disorder. This finding might be useful in the distinction of bacillary angiomatosis from Kaposi's sarcoma, because lesions from patients with Kaposi's sarcoma almost always contains HHV-8 DNA.

Indexed as

AdultAIDS-Related Opportunistic InfectionsAngiomatosis, BacillaryDiagnosis, DifferentialDNA, ViralFemaleHerpesvirus 8, HumanHumansMaleMiddle AgedPolymerase Chain ReactionSarcoma, KaposiDNA, Viral

Identifiers

PMID10748868
PMCPMC395720
OpenAlexW1965745203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.