Evidence map›Paper›PMID 10747137›Full record

ArticleJournal of clinical microbiology2000

Development of a serological test for Haemophilus ducreyi for seroprevalence studies.

C Elkins, K Yi, B Olsen, C Thomas, K Thomas, S Morse

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

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  5. The laboratory diagnosis of Haemophilus ducreyi.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2005
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

C ElkinsDepartments of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
K Yi
B Olsen
C Thomas
K Thomas
S Morse
Centers for Disease Control and Prevention · USUniversity of North Carolina at Chapel Hill · US

Funding

Trichomonas Typing SystemU19AI031496 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOBBS, MARCIA METZGAR · 1995 to 2014
$24.9M
IMMUNOBIOLOGY OF HEMOGLOBIN/HEME RECEPTORS OF H DUCREYIR29AI040263 · NIAID · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI ELKINS, CHRISTOPHER · 1996 to 2000
$97k
THE EPIDEMIOLOGY OF STDS IN RURAL NORTH CAROLINAU01AI031496 · NIAID · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI WYRICK, PRISCILLA B · 1991 to 1994
–
NIAID NIH HHS AI 31496NIAID NIH HHS R29-AI 40263NIAID NIH HHS U19 AI031496
6 · The paper itself

Abstract

We developed a new enzyme immunoassay (rpEIA) for use in determining the seroprevalence of chancroid. Three highly conserved outer membrane proteins from Haemophilus ducreyi strain 35000 were cloned, overexpressed, and purified from Escherichia coli for use as antigens in the rpEIA. Serum specimens from patients with and without chancroid were assayed to determine optimum sensitivity and specificity and to establish cutoff values. On the basis of these data, rpEIA was found to be both sensitive and specific when used to test a variety of serum specimens from patients with genital ulcers and urethritis and from healthy blood donors.

Indexed as

Immunoenzyme TechniquesAntibodies, BacterialAntigens, BacterialBacterial Outer Membrane ProteinsChancroidCloning, MolecularHaemophilus ducreyiHumansRecombinant ProteinsSensitivity and SpecificitySeroepidemiologic StudiesAntibodies, BacterialAntigens, BacterialBacterial Outer Membrane ProteinsRecombinant Proteins

Identifiers

PMID10747137
PMCPMC86480
OpenAlexW2169158441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.