Evidence map›Paper›PMID 10741993›Full record

ArticleBMJ (Clinical research ed.)2000

How many deaths have been avoided through improvements in cancer survival?

M A Richards, D Stockton, P Babb, M P Coleman

Open access · bronzeAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 81 citations in OpenAlex.

  1. Trial
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  8. Sexual and fertility-related adverse effects of medicinal treatment for cancer; a national evaluation among medical oncologists.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
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  12. Article
  13. Melatonin anticancer effects: review.International journal of molecular sciences · 2013
    Article
  14. Article
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  18. Article
  19. Article
  20. A qualitative study of delay among women reporting symptoms of breast cancer.The British journal of general practice : the journal of the Royal College of General Practitioners · 2001
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

M A RichardsDepartment of Palliative Medicine, St Thomas's Hospital, London SE17 7EH, UK.
D Stockton
P Babb
M P Coleman
St Thomas' Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate how many deaths from cancer have been avoided in England and Wales because of recent improvements in survival.

designAnalysis of national statistics.

settingEngland and Wales. SUBJECTS: 1.5 million adults with diagnosis of one of 47 different cancers during 1981-5 or 1986-90.

main outcome measuresReduction in number of cancer deaths within five years of diagnosis among patients with cancer diagnosed during 1986-90 compared with patients with cancer diagnosed during 1981-5.

results17 041 deaths were avoided within five years of diagnosis among patients with cancer diagnosed during 1986-90. This represents 3.3% of the cancer deaths that would have been expected if survival had been the same as for patients with cancer diagnosed during 1981-5. Two thirds of the avoided deaths arose from improvements in survival for just five cancers: female breast cancer (4822), cancers of the colon (2560), rectum (1090), and bladder (1157), and melanoma of the skin (1098). The largest proportionate reductions in excess deaths were for melanoma of the skin (23%) and cancers of the testis (17%) and bone (17%). About 12 000 (70%) of the avoided deaths arose among adults aged under 75 at death. Improvements in survival from cancers of lung, prostate, stomach, ovary, and brain were small: they accounted for 33% of all cancers but only 11% of avoided deaths.

conclusionsSmall gains in survival from common cancers save more lives than larger gains for uncommon cancers. If recent rates of improvement in cancer survival continue, about 24 000 deaths within five years of diagnosis would be avoided in patents aged under 75 by the year 2010, representing about a quarter of the government's overall target of 100 000 fewer cancer deaths.

Indexed as

AdultAgedAged, 80 and overAge FactorsEnglandFemaleHumansMaleNeoplasmsSurvival AnalysisWales

Identifiers

PMID10741993
PMCPMC27327
OpenAlexW2039345062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.