ArticleProceedings of the National Academy of Sciences of the United States of America2000
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Yeast secreted protein PgSCP interacts with citrus transcription factors CsFAR1 to enhance green mold resistance in fruit.Horticulture research · 2026Article
- p24 family proteins are critical for cell wall integrity, protein secretion, and virulence inmSphere · 2026Article
- Growth conditions shape the proteome and diversity ofCell surface (Amsterdam, Netherlands) · 2025Article
- p24-Tango1 interactions ensure ER-Golgi interface stability and efficient transport.The Journal of cell biology · 2024Article
- Engineering Cell Polarization Improves Protein Production inMicroorganisms · 2022Article
- Article
- Engineering vesicle trafficking improves the extracellular activity and surface display efficiency of cellulases inBiotechnology for biofuels · 2017Article
- Sec14-like phosphatidylinositol transfer proteins and the biological landscape of phosphoinositide signaling in plants.Biochimica et biophysica acta · 2016Review
- p24 family proteins: key players in the regulation of trafficking along the secretory pathway.Protoplasma · 2016Review
- Function of a p24 Heterodimer in Morphogenesis and Protein Transport in Penicillium oxalicum.Scientific reports · 2015Article
- Ricin trafficking in cells.Toxins · 2015Review
- Updating the Wnt pathways.Bioscience reports · 2014Article
- COPII and the regulation of protein sorting in mammals.Nature cell biology · 2011Review
- COPI budding within the Golgi stack.Cold Spring Harbor perspectives in biology · 2011Review
- Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum.Molecular biology of the cell · 2010Article
- Regulation and function of yeast PAS kinase: a role in the maintenance of cellular integrity.Cell cycle (Georgetown, Tex.) · 2009Article
- Localization and regional distribution of p23/TMP21 in the brain.Neurobiology of disease · 2008Article
- The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus.The Journal of cell biology · 2008Article
- Identification of yeast proteins necessary for cell-surface function of a potassium channel.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Disparate effects of p24alpha and p24delta on secretory protein transport and processing.PloS one · 2007Article
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8 authors.
Funding
Abstract
To investigate the factors involved in the sorting of cargo proteins into COPII endoplasmic reticulum (ER) to Golgi apparatus transport vesicles, we have created a strain of S. cerevisiae (p24Delta8) that lacks all eight members of the p24 family of transmembrane proteins (Emp24p, Erv25p, and Erp1p to Erp6p). The p24 proteins have been implicated in COPI and COPII vesicle formation, cargo protein sorting, and regulation of vesicular transport in eukaryotic cells. We find that p24Delta8 cells grow identically to wild type and show delays of invertase and Gas1p ER-to-Golgi transport identical to those seen in a single Deltaemp24 deletion strain. Thus, p24 proteins do not have an essential function in the secretory pathway. Instead, they may serve as quality control factors to restrict the entry of proteins into COPII vesicles.
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