Evidence map›Paper›PMID 10736861›Full record

ArticleThe Analyst1999

Polarization-based oxygen sensor.

I Gryczynski, Z Gryczynski, G Rao, J R Lakowicz

Open access · greenAbstract read
In one paragraph

Article in The Analyst, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 24 citations in OpenAlex.

  1. Tissue Factor-Targeted "OFrontiers in oncology · 2020
    Article
  2. Real-time local oxygen measurements for high resolution cellular imaging.Journal of molecular and cellular cardiology · 2019
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

I GryczynskiUniversity of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, Baltimore 21201, USA.
Z Gryczynski
G Rao
J R Lakowicz
University of Maryland, Baltimore · US

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
MINIMALLY INVASIVE IN VIVO GLUCOSE MONITORINGR01RR010955 · NCRR · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI RAO, GOVIND · 1995 to 1998
–
PROTEIN ENGINEERED GLUCOSE SENSORR01RR014170 · NCRR · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI RAO, GOVIND · 1998 to 1999
–
NCRR NIH HHS P41 RR008119NCRR NIH HHS RR-08119NCRR NIH HHS RR-10955NCRR NIH HHS RR-14170
6 · The paper itself

Abstract

A new approach to oxygen sensing based on the luminescence polarization observed from a novel type of sensor is described. The oxygen sensor consists of an oxygen-sensitive silicone film containing tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) chloride [Ru(dpp)3Cl2] and an oxygen-insensitive film of Styryl 7 in poly(vinyl alcohol). Polarizers are used to select orthogonally polarized emission components from Ru(dpp)3Cl2 and Styryl 7. The polarization of the combined emission was found to be highly sensitive to the partial pressure of oxygen. This method of polarization sensing is generic and can be used with any fluorophore which displays an analyte-dependent change in intensity.

Indexed as

Fluorescence PolarizationOxygenOxygen

Identifiers

PMID10736861
PMCPMC6814009
OpenAlexW1982752403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.