ArticleBiophysical journal2000
F-actin retains a memory of angular order.
Article in Biophysical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Myosin-5 varies its steps along the irregular F-actin track.bioRxiv : the preprint server for biology · 2023Article
- Molecular origins of cofilin-linked changes in actin filament mechanics.Journal of molecular biology · 2013Article
- Coarse-graining provides insights on the essential nature of heterogeneity in actin filaments.Biophysical journal · 2012Article
- Malaria parasite actin polymerization and filament structure.The Journal of biological chemistry · 2010Article
- Development of free-energy-based models for chaperonin containing TCP-1 mediated folding of actin.Journal of the Royal Society, Interface · 2008Review
- Problems in fitting high resolution structures into electron microscopic reconstructions.HFSP journal · 2008Article
- Large-scale models reveal the two-component mechanics of striated muscle.International journal of molecular sciences · 2008Article
- The structure of bacterial ParM filaments.Nature structural & molecular biology · 2007Article
- The alpha-helix, an overlooked molecular motor.Protoplasma · 2005Review
- Fluorescence depolarization of actin filaments in reconstructed myofibers: the effect of S1 or pPDM-S1 on movements of distinct areas of actin.Biophysical journal · 2004Article
- Order, disorder, and perturbations in actin-aldolase rafts.Biophysical journal · 2003Article
- An atomic model of actin filaments cross-linked by fimbrin and its implications for bundle assembly and function.The Journal of cell biology · 2001Article
- Actin depolymerizing factor stabilizes an existing state of F-actin and can change the tilt of F-actin subunits.The Journal of cell biology · 2001Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Modifications can be made to F-actin that do not interfere with the binding of myosin but inhibit force generation, suggesting that actin's internal dynamics are important for muscle contraction. Observations from electron microscopy and x-ray diffraction have shown that subunits in F-actin have a relatively fixed axial rise but a variable twist. One possible explanation for this is that the actin subunits randomly exist in different discrete states of "twist, " with a significant energy barrier separating these states. This would result in very slow torsional transitions. Paracrystals impose increased order on F-actin filaments by reducing the variability in twist. By looking at filaments that have recently been dissociated from paracrystals, we find that F-actin retains a "memory" of its previous environment that persists for many seconds. This would be consistent with slow torsional transitions between discrete states of twist.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.